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Blog - Life Sciences - Page 5
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Product of the Month: Indocyanine Green (ICG) Dyes
Indocyanine Green (ICG) dye, a material approved by the FDA for various applications, is a powerful tool for imaging in live cells and tissues.
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A Cyclo-RGD Peptide for the Preparation of Tumor Mimics
The 2D monolayer cell culture model is widely applied for drug screening. However, this approach is frequently not able to adequately mimic the in vivo response.
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Lysine Dendrons
We now offer a series of Lysine dendrons for chemoselective functionalization of molecules containing carbonyl groups. These multivalent molecules carry diverse types of moieties, such as amine- or hydroxyl-groups, DOTA chelators or triphenylphosphonium (TPP) cations.
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Omniligase-1 for Efficient Peptide Ligation
Omniligase-1 enables efficient and racemization-free ligation of two side-chain unprotected peptide fragments at many different positions. Test this innovative enzyme developed by EnzyPep B.V. using the complementary model peptides included in our kit!
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Chlorotoxin & Biotin-Chlorotoxin
Chlorotoxin is a chloride channel blocker which has been found in the venom of the Egyptian scorpionLeiurus quinquestriatus.
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Fast and Easy Protease Kinetics with Asymmetric Rhodamine 110 Substrates
Asymmetric Rhodamine 110 protease substrates are used for the determination of protease kinetics. The asymmetric structure of these dyes greatly simplifies the determination of enzyme kinetics, while the properties of Rhodamine 110 facilitate an uncomplicated readout.
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Markers for the Quality of Food
Maillard Reaction Products (MRPs) result from the reaction of Arg and Lys side chains with reducing carbohydrates. MRPs are valuable markers for food quality and are used in many different branches of industry such as food, pharma, cosmetics and biochemistry.
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Fmoc-Phe-Aca: Fluorescent Internalization Reporter for Cell Penetrating Peptides (CPPs)
The Fmoc-L-Phe-Aca pseudo-dipeptide is a useful reporter group for the successful internalization of CPPs. Phe quenches the fluorescence of Aca. Internalization of the peptide containing Phe-Aca leads to proteolytic cleavage of the Phe-Aca bond and thus to fluorescence.
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New Statin Analogues: Super-Threonine Derivatives
A set of new statin analogues, so called Super-Threonines, is available consisting of Fmoc protected L-enantiomers with all possible 4 stereoisomers of chiral centers in the side chain. They appear in nature as bridge building element in cyclodepsipeptides, like pipecolidepsin A, a compound which shows relevant cytotoxic activity in three human tumor cell lines (lung, colon, breast) and has unique structural features.
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