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Mal-cyclobutane-1,1-dicarboxamide-Ala-PAB-PNP
Chemical name: 5-maleimidopentyl-cyclobutane-1,1-dicarboxamide-alanyl-(4-aminobenzyl)-(4-nitrophenyl)-carbonate // Synonyms: (S)-4-(2-(1-(5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentylcarbamoyl)cyclobutanecarboxamido)propanamido)benzyl 4-nitrophenyl carbonate
- Product code:ADC1570
- CAS No.:2576471-35-5
- Formula:C32H35N5O10
- Storage temperature:-20°C
- Molecular weight:649.65 g/mol
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references
Discovery of Peptidomimetic Antibody–Drug Conjugate Linkers with Enhanced Protease Specificity. BinQing Wei, Janet Gunzner-Toste, Hui Yao, Tao Wang, Jing Wang, Zijin Xu, Jinhua Chen, John Wai, Jim Nonomiya, Siao Ping Tsai, Josefa Chuh, Katherine R. Kozak, Yichin Liu, Shang-Fan Yu, Jeff Lau, Guangmin Li, Gail D. Phillips, Doug Leipold, Amrita Kamath, Dian Su, Keyang Xu, Charles Eigenbrot, Stefan Steinbacher, Rachana Ohri, Helga Raab, Leanna R. Staben, Guiling Zhao, John A. Flygare, Thomas H. Pillow, Vishal Verma, Luke A. Masterson, Philip W. Howard, Brian Safina; J. Med. Chem. 2018; 61(3): 989-1000. DOI: org/10.1021/acs.jmedchem.7b01430.
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