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Boc-L-Lys(Aloc)-OH*DCHA
Chemical name: N-alpha-t-Butyloxycarbonyl-N-epsilon-allyloxycarbonyl-L-lysine dicyclohexylamine salt // Synonyms: Boc-Lys(Aloc)-OH*DCHA, Boc-L-Lys(Alloc)-OH*DCHA, Boc-Lys(Alloc)-OH*DCHA
- Product code:BAA1103
- CAS No.:110637-52-0
- Storage temperature:2-8°C
- Formula:C15H26N2O6*C12H23N
- Molecular weight:330.38*181.32 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99,9%
from $50.00
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy, Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. Benny Gerber,
and Assaf Friedler; Angew. Chem. Int. Ed. 2014; 53: 9450-9455. DOI: 10.1002/anie.201402789.
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