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H-L-Lys(Tmoc)-OH*HCl
Chemical name: N-epsilon-Trimethylsilylmethyloxycarbonyl-L-lysine hydrochloride salt // Synonyms: TMSK, (1S)-1-carboxy-5-({[(trimethylsilyl)methoxy]carbonyl}amino)pentan-1-aminium chloride, H-Lys(OCOCH2SiMe3) HCl salt, N6-(((Trimethylsilyl)methoxy)carbonyl)-l-lysine,H-Lys(Tmoc)-OH*nHCl
- Product code:HAA9205
- CAS No.:2756444-49-0 net
- Formula:C11H25ClN2O4Si
- Molecular weight:276.41*36.46 g/mol
- Purity :min. 98%
- Enantiomeric Purity:min. 99,7%
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description
This non-canonical amino acid can be genetically incorporated into proteins for protein-protein and ligand-protein interaction studies by NMR.
references
Genetic Encoding of N6-(((Trimethylsilyl)methoxy)carbonyl)-L-lysine for NMR Studies of Protein-Protein and Protein Ligand Interactions; E. H. Abdelkader, H. Qianzhu, Y. J. Tan, L. A. Adams, T. Huber, G. Otting; J. Am. Chem. Soc. 2021; 143(2): 1133-1143. https://doi.org/10.1021/jacs.0c11971.
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