N3-L-Lys(Mtt)-OH

Chemical name: (S)-2-Azido-6-[(4-methyltrityl)amino]hexanoic acid // Synonyms: N3-Lys(Mtt)-OH, alpha-Azido-N-epsilon-p-metyltrityl-L-lysine

  • Product code:HAA2880
  • CAS No.:1333231-26-7
  • Formula:C26H28N4O2
  • Storage temperature:2-8°C
  • Molecular weight:428.53 g/mol
  • Purity :min. 99%
  • Enantiomeric Purity:min. 99,7%

from $135.00

Grouped product items
Qty Packing unit Price SKU Availability
500 mg
$135.00
HAA2880.0500
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1 g
$210.00
HAA2880.0001
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5 g
$750.00
HAA2880.0005
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25 g
$3,000.00
HAA2880.0025
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description

Amino acid building block for introducing azido functions into peptide sequences at the N-terminal position. The azido moiety can be employed in standard click conjugation or serve as masked amino function, which it can be transferred into by reduction with phosphines.

references

alpha,beta-Diamino Acids: Biological Significance and Synthetic Approaches; Alma Viso, Roberto Fernández de la Pradilla, Ana García, and Aida Flores; Chemical Reviews 2005; 105(8): 3167-3196. DOI: 10.1021/cr0406561.

Update 1 of: alpha,beta-Diamino Acids: Biological Significance and Synthetic Approaches; Alma Viso, Roberto Fernández de la Pradilla, Mariola Tortosa, Ana García, and Aida Flores; Chem. Rev. 2011; 111: PR1-PR42. DOI 10.1021/cr100127y.

Orthogonally Protected Cyclo-ß-tertapeptides as Solid-Supported Scaffolds for the Synthesis of Glycoclusters; Pasi Virta, Marika Karskela, Harri Lönnberg; J.Org.Chem 2006; 71: 1989-1999.

Stereocontrolled Route to Vicinal Diamines by [3.3] Sigmatropic Rearrangement of Allyl Cyanate: Asymmetric Synthesis of anti-(2R,3R)-and syn-(2R,3S)-2,3-Diaminobutanoic Acids; Yoshiyasu Ichikawa, Haruka Egawa, Takashi Ito, Minoru Isobe, Keiji Nakano, and Hiyoshizo Kotsuki; Org.Lett. 2006; 8(25): 5737-5740.

Efficient Synthesis of orthogonally protected ant-2,3-diamino acids; Stefania Capone, Annalisa Guaregna, Giovanni Palumbo, Silvana Pedatella; Tetrahedron 2005; 61: 6575-6579.


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