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Continue to Iris Biotech GmbHSend request to US distributorChemical name: 4-(((9H-fluoren-9-yl)methoxy)carbonylamino)-1-methyl-1H-pyrrole-2-carboxylic acid // Synonyms: 4-(Fmoc-amino)-1-methylpyrrole-2-carboxylic acid
from $157.50
Fmoc-Py-OH is a building block for the synthesis of pyrrole-imidazole polyamides (PIPs). These polyamides are synthetic ligands that have an affinity and specificity for DNA comparable to those of many naturally occurring DNA binding proteins.
Fmoc Solid Phase Synthesis of Polyamides Containing Pyrrole and Imidazole Amino Acids; N. . Wurtz, J. M. Turner, E. E. Baird, P. B. Dervan; Org. Lett. 2001; 3(8): 1201-1203. https://doi.org/10.1021/ol0156796.
A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts; G. N. Pandian, Y. Nakano, S. Sato, H. Morinaga, T. Bando, H. Nagase, H.Sugiyama; Scientific Reports 2012; 544. https://doi.org/10.1038/srep00544.
Discovery of Pyrrole-imidazole Polyamides as PD-L1 Expression Inhibitors and Their Anticancer Activity via Immune and Nonimmune Pathways; M. Wang, X. Ma, K. Zhou, H. Mao, J. Liu, X. Xiong, X. Zhao, S. Narva, Y. Tanaka, Y.Wu, C. Guo, H. Sugiyama, W. Zhang; J. Med. Chem. 2021; 64(9): 6021-6036. https://doi.org/10.1021/acs.jmedchem.1c00120.
Pyrrole-Imidazole Polyamides: Manual Solid-Phase Synthesis; S. M. Pauff, A. J. Fallows; S. P. Mackay, W. Su, P. M. Cullis, G. A. Burley; Curr. Protoc. Nucleic Acid Chem. 2015; 63: 8.10.1-8.10.41. https://doi.org/10.1002/0471142700.nc0810s63.
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