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Fmoc-N(Mmsb)-Gly-OH
Chemical name: N-alpha (9-Fluorenylmethyloxycarbonyl)-N-alpha-(2-methoxy-4-(methylsulfinyl)benzyl)-glycine // Synonyms: 2-((((9H-fluoren-9-yl)methoxy)carbonyl)(2-methoxy-4-(methylsulfinyl)benzyl)amino)acetic acid, Safety-Catch Glycine
- Product code:FAA7340
- CAS No.:2389064-40-6
- Formula:C26H25NO6S
- Storage temperature:2-8°C
- Molecular weight:479.54 g/mol
from $218.75
description
A Fmoc protected L-Glycine for SPSS, with an Msib protected amino function. This building block may be used to protect an amide bond during peptoid synthesis. The Mmsb protecting group is removed by reduction of the sulfoxide, followed by acidolysis with TFA.
references
2-Methoxy-4-methylsulfinylbenzyl: A Backbone Amide Safety-Catch Protecting Group for the Synthesis and Purification of Difficult Peptide Sequences. Marta Paradís-Bas, Judit Tulla-Puche, and Fernando Albericio; Chem. Eur. J. 2014; 20: 15031–15039. DOI: 10.1002/chem.201403668
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