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Fmoc-L-Glu-OPP
Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-glutamic acid alpha-(2-phenylisopropyl ester) // Synonyms: Fmoc-Glu-O-2PhiPr, Fmoc-Glu-OPis, (S)-4-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-oxo-5-(2-phenylpropan-2-yloxy)pentanoic acid, Fmoc-Glu-OPP
- Product code:FAA7380
- CAS No.:207305-97-3
- Formula:C29H29NO6
- Molecular weight:487.54 g/mol
from $343.75
description
A Glutamic acid building block with free side chain and PP protected alpha-carboxylic acid function. The 2-phenylisopropyl protecting group can be deprotected with 1% TFA in dichloromethane. PP protected amino acids are also less prone towards aspartamide formation.
references
C.Yue et al.; Tetrahedron Lett. 1993; 34: 323.
F.Dick et al.; Peptides 1996; Proceedings of the 24th European Peptide Symposium Edinborough, Scotland, p.339.
R.Ramage, R.Epton, eds. Mayflower Scientific Ltd., England (1998)
M.Mergler et al.; J.Pept.Sci. 2003; 9: 36.
S.M.Ocampo et al.; Org.Lett. 2005; 7: 4349.
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