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Fmoc-L-Lys(pNZ)-OH
Chemical name: N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(((4-nitrobenzyl)oxy)carbonyl)-L-lysine // Synonyms: Fmoc-Lys(pNZ)-OH
- Product code:FAA8820
- CAS No.:174653-61-3
- Formula:C29H29N3O8
- Storage temperature:2-8°C
- Molecular weight:547.56 g/mol
- Purity :min. 98%
from $135.00
description
Semipermanently side-chain protected Lys for prevention of undesired alpha-Fmoc removal during SPPS. It can be removed selectively with SnCl2/HCl in DMF.
references
Semipermanent p-nitrobenzyloxycarbonyl (pNZ) protection of Orn and Lys side chains: prevention of undesired alpha-Fmoc removal and application to the synthesis of cyclic peptides; S. Isidro-Llobet, M. Álvarez, F. Albericio; Tetrahedron Lett. 2005; 46(45): 7733-7736. https://doi.org/10.1016/j.tetlet.2005.09.043.
Solid-Phase Synthesis of Cyclic Lipopeptidotriazoles; S. Vilà, C. Camó, E. Figueras, E. Badosa, E. Montesinos, M. Planas, L. Feliu; Eur. J. Org. Chem. 2014; 22: 4785-4794. https://doi.org/10.1002/ejoc.201402111.
Chemoselectively Addressable Template: A Valuable Tool for the Engineering of Molecular Conjugates; E. Garanger, D. Boturyn, O. Renaudet, E. Defrancq, P. Dumy; J. Org. Chem. 2006; 71(6): 2402-2410. https://doi.org/10.1021/jo0525480.
A Lasso-Inspired Bicyclic Peptide: Synthesis, Structure and Properties; H. Martin-Gómez, F. Albericio, J. Tulla-Puche; Chem. Eur. J. 2018; 24(72): 19250-19257. https://doi.org/10.1002/chem.201803899.
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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