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Boc-L-Thr[Psi(Me,Me)Pro]-OH
Chemical name: (4S,5R)-3-(tert-butyloxycarbonyl)-2,2,5-trimethyloxazolidine-4-carboxylic acid // Synonyms: Boc-Thr[Psi(Me,Me)Pro]-OH, N,O-Isopropylidene-N-tert-butoxycarbonyl-L-threonine
- Product code:PSI1640
- CAS No.:143364-85-6
- Formula:C12H21NO5
- Storage temperature:2-8°C
- Molecular weight:259.30 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99.7%
from $87.50
description
Threonine-derived Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids. See also the Fmoc-derivative FAA8695.
references
Reference:
Scope and limitations of pseudoprolines as individual amino acids in peptide synthesis; D. A. Senko, N. D. Timofeev, I. E. Kasheverov, I. A. Ivanov; Amino Acids 2021; 53: 665-671. https://doi.org/10.1007/s00726-021-02973-1.
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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