Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
USD
Quick contact
Please send me more information about
COMU ®
Chemical name: 1-[1-(Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino]-uronium hexafluorophosphate
- Product code:RL-1175
- CAS No.:1075198-30-9
- Formula:C12H19N4O4PF6
- Storage temperature:2-8°C
- Molecular weight:428.26 g/mol
from $113.75
description
COMU is an efficient coupling reagent requiring one equivalent of base during bond formation as it liberates morpholine. Typical applications are amide bond formation, eg. in both solution and solid phase synthesis at room temperature or with conventional heating or microwave. Minimized racemization. Supposed to be non-allergenic. Couplings can be monitored visually or colourimetrically due to color change from yellow to orange; the reagent shows excellent solubility in DMF and NMP.
references
R. Subirós-Funosas, R. Prohens, R. Barbas, A. El-Faham, F. Albericio; Chem. Eur. J. 2009; 15: 9394-9403.
A. El-Faham, F. Albericio; J. Pept. Sci. 2010; 16: 6-9.
R. Subiros-Funosas, S. N. Khattab, L. Nieto-Rodriguez, A. El-Faham, F. Albericio; Aldrichim. Acta 2013; 46: 21-40.
A. El-Faham, R. S. Funosas, R. Prohens, F. Albericio; Chem. Eur. J. 2009; 15: 9404-9416.
R. Subiros-Funosas, G. A. Acosta, A. El-Faham, F. Albericio; Tetrahedron Lett. 2009; 50: 6200-6202.
A. El-Faham and F. Albericio, J. Org. Chem. 2008; 73: 2731.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
We found other products you might like!
