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T-BEC
Chemical name: 1-tert-Butyl-3-ethylcarbodiimide // Synonyms: N-tert-butyl-N-ethylmethanediimine, TBEC
- Product code:RL-3910
- CAS No.:1433-27-8
- Formula:C7H14N2
- Storage temperature:2-8°C
- Molecular weight:126.20 g/mol
from $156.25
description
It has been reported that DIC can react with OxymaPure to render an oxadiazole compound with the concomitant formation of HCN. The reaction of TBEC with OxymaPure is exempt from HCN formation.
references
Reference:
Amide Formation: Choosing the Safer Carbodiimide in Combination with OxymaPure to Avoid HCN Release; S. R. Manne, O. Luna, G. A. Acosta, M. Royo, A. El-Faham, G. Orosz, B. G. de la Torre, F. Albericio; Org. Lett. 2021; 23: 6900-6904. https://doi.org/10.1021/acs.orglett.1c02466.
tert-Butylethylcarbodiimide as an Efficient Substitute for Diisopropylcarbodiimide in Solid-Phase Peptide Synthesis: Understanding the Side Reaction of Carbodiimides with OxymaPure; S. R. Manne, D. C. Akintayo, O. Luna, A. El-Faham, B. G. de la Torre, F. Albericio; Org. Process Res. Dev. 2022. https://doi.org/10.1021/acs.oprd.2c00220
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Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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