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Fmoc-L-Lys(pNZ)-OH
Nom chimique: N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(((4-nitrobenzyl)oxy)carbonyl)-L-lysine // Synonymes: Fmoc-Lys(pNZ)-OH
- n° Art.:FAA8820
- n° CAS:174653-61-3
- Formule:C29H29N3O8
- Storage temperature:2-8°C
- Masse moléculaire:547,56 g/mol
- Pureté:min. 98%
from 108,00 €
description
Semipermanently side-chain protected Lys for prevention of undesired alpha-Fmoc removal during SPPS. It can be removed selectively with SnCl2/HCl in DMF.
references
Semipermanent p-nitrobenzyloxycarbonyl (pNZ) protection of Orn and Lys side chains: prevention of undesired alpha-Fmoc removal and application to the synthesis of cyclic peptides; S. Isidro-Llobet, M. Álvarez, F. Albericio; Tetrahedron Lett. 2005; 46(45): 7733-7736. https://doi.org/10.1016/j.tetlet.2005.09.043.
Solid-Phase Synthesis of Cyclic Lipopeptidotriazoles; S. Vilà, C. Camó, E. Figueras, E. Badosa, E. Montesinos, M. Planas, L. Feliu; Eur. J. Org. Chem. 2014; 22: 4785-4794. https://doi.org/10.1002/ejoc.201402111.
Chemoselectively Addressable Template: A Valuable Tool for the Engineering of Molecular Conjugates; E. Garanger, D. Boturyn, O. Renaudet, E. Defrancq, P. Dumy; J. Org. Chem. 2006; 71(6): 2402-2410. https://doi.org/10.1021/jo0525480.
A Lasso-Inspired Bicyclic Peptide: Synthesis, Structure and Properties; H. Martin-Gómez, F. Albericio, J. Tulla-Puche; Chem. Eur. J. 2018; 24(72): 19250-19257. https://doi.org/10.1002/chem.201803899.
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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