Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Contact rapide
Veuillez m'envoyer plus d'informations sur
H-L-Lys(Palm)-OMe*HCl
Nom chimique: Methyl N-epsilon-palmitoyl-L-lysine hydrochloride // Synonymes: Methyl N6-palmitoyl-L-lysinate, Methyl N-epsilon-palmitoyl-L-lysinate, Methyl N6-palmitoyl-L-lysine hydrochloride, H-Lys(Palm)-OMe*HCl, N6-Palmitoyl-L-lysine methyl esterhydrochloride, 890082-89-0 ( net CAS), H-Lys(Palm)-OMe*HCl
- n° Art.:HAA9225
- n° CAS:890026-44-5
- Formule:C23H46N2O3*HCl
- Storage temperature:2-8°C
- Masse moléculaire:398,63*36,46 g/mol
- Pureté:min. 98%
- Pureté Énantiomérique:min. 99,7%
from 108,00 €
description
This fatty-acid modified Lysine building block is investigated for its use in surfactant, micelle, and nanoparticle research. It can be used to introduce lipophilic chains into peptides. Fatty Amino Acids are reported to improve the pharmacokinetic and pharmacologic properties of peptide APIs and other biopharmaceuticals. Serum lifetimes can be drastically improved as the fatty acid residue helps to bind temporarily to serum albumin. This enhances stability towards proteolytic degradation.
references
Cationic surfactants from lysine: Synthesis, micellization and biological evaluation; L. Perez, A. Pinazo, M. Teresa Garcia, M. Lozano, A. Manresa, M. Angelet, M. Pilar Vinardell, M. Mitjans, R. Pons, M. Rosa Infante; Eur. J. Med. Chem. 2009; 44(5): 1884-1892. https://doi.org/10.1016/j.ejmech.2008.11.003.
Self Assembly of pH-Sensitive Cationic Lysine Based Surfactants; A. Mezei, L. Perez, A. Pinazo, F. Comelles, M. Rosa Infante, R. Pons; Langmuir 2012; 28(49): 16761-16771. https://doi.org/10.1021/la304117f.
Basic peptides containing fatty acids and their antibacterial activity; K. Vogler, P. Lanz, P. Quitt, R. O. Studer, W. Lergier, E. Boehni, B. Frust; Helv. Chim. Acta 1964; 47(2): 526-44.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Besoin d'informations supplémentaires sur ce produit?
entrer en contact
Brochures et dépliants
Des produits qui pourraient également vous intéresser!
