Fmoc-D-Lys(MeDmb)-OH

Nom chimique: (2R)-6-{[1-(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)ethyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid

  • n° Art.:FAA8845
  • Formule:C29H32N4O7
  • Storage temperature:2-8°C
  • Masse moléculaire:548,60 g/mol
  • Pureté:min.98%
  • Pureté Énantiomérique:min.99,9%

from 126,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
1 g
126,00 €
FAA8845.1000
<10 jour ouvrables
5 g
450,00 €
FAA8845.5000
sur demande
25 g
1 800,00 €
FAA8845.9025
sur demande
description

Novel Lysine building-block for SPPS bearing a new side-chain protecting-group. MeDmb is an orthogonal protecting group, stable under acidic and basic conditions used during SPPS and can be cleaved by a mild solution of 2% hydrazine hydrate in DMF and 2% hydroxylamine in DMF. The advantage of MeDmb over dimedone derivatives is the increased hydrophilicity, which should increase their solubility in a broad range of solvents, including green solvents.


references

Scope and Limitations of Barbituric and Thiobarbituric Amino Acid Derivatives as Protecting Groups for Solid-Phase Peptide Synthesis: Towards a Green Protecting Group; S. Ramkisson, H. H. Al-Rasheed, K. A. Dahlous, B. G. De La Torre, A. El-Faham, F. Albericio; Chem. Select 2021; 6(26): 6626-6630. https://doi.org/10.1002/slct.202101539


* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.

Besoin d'informations supplémentaires sur ce produit?

entrer en contact

Contact rapide

Veuillez m'envoyer plus d'informations sur

Des produits qui pourraient également vous intéresser!