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H-L-Lys(MeTz-PhAc)-OH*TFA
Nom chimique: N-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl)acetyl)-L-lysine TFA salt // Synonymes: Tetrazin-lysine trifluoracetate, H-Lys(MeTz-PhAc)-OH*TFA
- n° Art.:HAA9170
- n° CAS:2578384-82-2 (net)
- Formule:C17H22N6O3*CF3COOH
- Storage temperature:-20°C
- Masse moléculaire:358,40*114,02 g/mol
from 675,00 €
description
Lysine building block carrying tetrazine suitable for 3rd generation Click conjugation with any suitable dienophile.
references
Inverse electron demand Diels-Alder (IEDDA) reactions in peptide chemistry; M. Pagel; Journal of peptide science : an official publication of the European Peptide Society 2019; 25: e3141. https://doi.org/10.1002/psc.3141
Bioorthogonal Fluorescence Turn-On Labeling Based on Bicyclononyne-Tetrazine Cycloaddition Reactions that Form Pyridazine Products; S. J. Siegl, J. Galeta, R. Dzijak, M. Dracinsky and M. Vrabel; Chempluschem 2019; 84: 493-497. https://doi.org/10.1002/cplu.201900176
An Extended Approach for the Development of Fluorogenic trans-Cyclooctene-Tetrazine Cycloadditions; S. J. Siegl, J. Galeta, R. Dzijak, A. Vazquez, M. Del Rio-Villanueva, M. Dracinsky and M. Vrabel; Chembiochem : a European journal of chemical biology 2019; 20: 886-890. https://doi.org/10.1002/cbic.201800711
Advances in Tetrazine Bioorthogonal Chemistry Driven by the Synthesis of Novel Tetrazines and Dienophiles; H. Wu and N. K. Devaraj; Acc Chem Res 2018; 51: 1249-1259. https://doi.org/10.1021/acs.accounts.8b00062
Bio-orthogonal Fluorescent Labelling of Biopolymers through Inverse-Electron-Demand Diels-Alder Reactions; E. Kozma, O. Demeter and P. Kele; Chembiochem : a European journal of chemical biology 2017; 18: 486-501. https://doi.org/10.1002/cbic.201600607
Bicyclo[6.1.0]nonyne and tetrazine amino acids for Diels–Alder reactions; X. Li, Z. Liu and S. Dong; RSC Advances 2017; 7: 44470-44473. https://doi.org/10.1039/c7ra08136g
Inverse electron demand Diels-Alder reactions in chemical biology; B. L. Oliveira, Z. Guo and G. J. L. Bernardes; Chem Soc Rev 2017; 46: 4895-4950. https://doi.org/10.1039/c7cs00184c
Click Chemistry and Radiochemistry: The First 10 Years; J. P. Meyer, P. Adumeau, J. S. Lewis and B. M. Zeglis; Bioconjug Chem 2016; 27: 2791-2807. https://doi.org/10.1021/acs.bioconjchem.6b00561
Highly accelerated inverse electron-demand cycloaddition of electron-deficient azides with aliphatic cyclooctynes; J. Dommerholt, O. van Rooijen, A. Borrmann, C. F. Guerra, F. M. Bickelhaupt and F. L. van Delft; Nat Commun 2014; 5: 5378. https://doi.org/10.1038/ncomms6378
The inverse electron demand Diels-Alder click reaction in radiochemistry; T. Reiner and B. M. Zeglis; J Labelled Comp Radiopharm 2014; 57: 285-90. https://doi.org/10.1002/jlcr.3149
3,6-Substituted-1,2,4,5-tetrazines: tuning reaction rates for staged labeling applications; D. Wang, W. Chen, Y. Zheng, C. Dai, K. Wang, B. Ke and B. Wang; Org Biomol Chem 2014; 12: 3950-5. https://doi.org/10.1039/c4ob00280f
trans-Cyclooctene--a stable, voracious dienophile for bioorthogonal labeling; R. Selvaraj and J. M. Fox; Curr Opin Chem Biol 2013; 17: 753-60. https://doi.org/10.1016/j.cbpa.2013.07.031
Inverse electron demand Diels-Alder (iEDDA)-initiated conjugation: a (high) potential click chemistry scheme; A. C. Knall and C. Slugovc; Chem Soc Rev 2013; 42: 5131-42. https://doi.org/10.1039/c3cs60049a
The growing impact of bioorthogonal click chemistry on the development of radiopharmaceuticals; D. Zeng, B. M. Zeglis, J. S. Lewis and C. J. Anderson; J Nucl Med 2013; 54: 829-32. https://doi.org/10.2967/jnumed.112.115550
Biomedical applications of tetrazine cycloadditions; N. K. Devaraj and R. Weissleder; Acc Chem Res 2011; 44: 816-27. https://doi.org/10.1021/ar200037t
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All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
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