N3-Pen-Dde

Nom chimique: 2-(5-azido-1-hydroxypentylidene)-5,5-dimethylcyclohexane-1,3-dione // Synonymes: 5-azido-1-Dde-pentan-1-ol

  • n° Art.:RL-3280
  • n° CAS:1867129-38-1
  • Formule:C13H19N3O3
  • Storage temperature:2-8°C
  • Masse moléculaire:265,31 g/mol

from 125,00 €

Grouped product items
Nombre Unité de vente Prix SKU Disponibilité
250 mg
125,00 €
RL-3280.0250
sur demande
1 g
350,00 €
RL-3280.0001
sur demande
5 g
1 400,00 €
RL-3280.0005
sur demande
description

This cleavable linker is highly valuable for usage in protein enrichment and other applications. A linker based on the Dde protecting group leads to efficient release of targets under mild aqueous buffered conditions with 2% hydrazine.


references

Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues; M. Galibert, V. Piller, F. Piller, V. Aucagne and A. F. Delmas; Chem. Sci. 2015; 6: 3617-3623. https://doi.org/10.1039/C5SC00773A


Mapping the Binding Site of BMS-708163 on gamma-Secretase with Cleavable Photoprobes; N. Gertsik, C. W. Am Ende, K. F. Geoghegan, C. Nguyen, P. Mukherjee, S. Mente, U. Seneviratne, D. S. Johnson and Y. M. Li; Cell Chem Biol 2017; 24: 3-8. https://doi.org/10.1016/j.chembiol.2016.12.006

Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag; M. E. Griffin, E. H. Jensen, D. E. Mason, C. L. Jenkins, S. E. Stone, E. C. Peters and L. C. Hsieh-Wilson; Mol. BioSyst. 2016; 12: 1756-1759. https://doi.org/10.1039/C6MB00138F


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