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What’s new? Don’t miss innovative building blocks and latest technologies – have a look at our new products flyer and discover our portfolio additions from January to June 2024!
A heart of gold! Metals and ores - see here how their surfaces can be equipped with bifunctional organic linker molecules and thus be turned into modifiable biocompatible materials.
Curious about our latest portfolio additions from January to June 2023? Discover our New Products Flyer and check out the summary of recent product highlights! Get in contact for more details!
Our monofunctionalized dextrans are enriching the toolbox of polymer therapeutics – Dextrans benefit of excellent solubility, biocompatibility, biodegradability, and non-immunogenicity.
The HaloTag®, SNAP-Tag® and CLIP-Tag TM represent versatile tools for the specific, covalent attachment of in principle any molecule of choice to a protein of interest. Discover our substrates!
Iris Biotech offers a variety of (functionalized) biotin and desthiobiotin reagents reactive towards certain functional groups. Discover our growing portfolio and latest additions.
Placing Dde as one terminal group of a linker and a functional group prone for conjugation as the other or using Dde as the central connective portion of a linker, allows for the creation of new bifunctional linkers.
Methods for proteomic mapping of cellular organelles or subdomains that avoid the necessity of cell lysis and purification by targeting specific subcellular regions have several advantages.
a) Catalyst-free Click Reaction
Cycloaddition reactions such as the [3+2] azide-alkyne and the [4+2] Diels-Alder reaction, are becoming common conjugation techniques. Applications range from imaging, drug design and development of sensors, thereby spanning the fields of chemical biology, material science, surface and polymer chemistry as well as many other fields.
Introduced in 2002, the copper-catalyzed variant of the azide-alkyne cycloaddition (CuAAC) reaction has found broad applicability in t...
Nanotechnology and nanobiotechnology using gold or silver particles, quantum dots or even magnetic particles are broadly diverse, rapidly expanding areas of study in medical diagnostics and therapeutics, sensoric and chemistry.
The presence of catalytic copper, limits the in vivo application of the Click this reaction for several reasons.
We offer custom synthesis of Strained Cyclooctynes and Substituted 1,2,4,5- Tetrazines as building blocks for fast Click reactions in the absence of any catalyst.
Tyramine compounds are converted to highly reactive radicals by horseradish peroxidase in presence of H2O2 which preferentially react with surface exposed tyrosines. Biotin Tyramide and Biotin-PEG-Tyramide therefore are ideal reagents used for tyrosine-/protein-biotinylation.