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PotM: MYTsA – A Novel Ynamide Coupling Reagent
Discover MYTsA as coupling reagent for peptide synthesis in “traditional”...
Read more...Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and...
Read more...Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis
Collect information about the most common side reactions during Fmoc SPPS and...
Read more...PotM: Versatile TentaGel® Resins
Discover the diversity of TentaGel® Resins! Read our blog to get more...
Read more...PotM: Cyclover-Amine for Peptide and Oligonucleotide Synthesis
Cyclophase Synthesis - Dissolve. React. Precipitate. Filter. Repeat! Make...
Read more...Bioisosteric Argininine Analogs
Same but different! Expand your possibilities for peptide modification and...
Read more...Protecting Groups in SPPS
Mix & Match. Discover typically employed protecting groups used to...
Read more...Amino-Li Resin – A Novel Solid Support
Shaken, not stirred. Amino-Li resin – a cross-linked polyacrylic amide...
Read more...Novel amino-Li resin for water-based solid-phase peptide synthesis
Amino-Li resin – a cross-linked polyacrylic amide solid support suitable...
Read more...Latest Products 2024 (Part 1)
What’s new? Don’t miss innovative building blocks and latest technologies...
Read more...Deprotection and Coupling in SPPS
Get the most out of your synthesis! Monitor your deprotection and coupling...
Read more...Bifunctional TentaGel® Resins
Encode beads with unique tags for combinatorial syntheses & screening....
Read more...Boc versus Fmoc for Solid Phase Peptide Synthesis
Wondering about the difference between Boc and Fmoc chemistry in solid phase...
Read more...Norbornenes – Will You Click Me?
Proposing norbornenes – strained, bicyclic alkenes for fast, copper-free,...
Read more...Phenylboronate Amino Acid Building Blocks
Boron is not boring at all! Today, we'll delve deeper into the exciting world...
Read more...Tougher Restrictions on DMF
REACH regulation for the handling of N,N-dimethylformamide (DMF), the most...
Read more...Glycosylated Asparagine Building Blocks for SPPS
Add glycans to your proteins with our ready-to-use Fmoc asparagine building...
Read more...Automated Peptide Synthesis
The discovery of the Merrifield peptide synthesis paved the way for automated...
Read more...Peptide Nucleic Acids as Stable DNA and RNA Analogs
One molecule, two identities: PNAs are composed of nucleobases arranged on a...
Read more...PotM: Next Generation Lysine Side Chain Protecting Groups
Sick of Lysine side chain protecting groups jumping around, yielding...
Read more...Conjugating Natural Products (3)
The potential of natural products of daily life, such as 6-shogaol from...
Read more...Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation
Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so...
Read more...PotM: Safety Catch - Orthogonally Protected Amino Acids
Add a new dimension of orthogonality to your peptide synthesis by using...
Read more...Coupling Reagents
Coupling Reagents are required for the formation of an amide or ester bond....
Read more...Let’s Talk Iris
You want to get an overview about the different Click technologies as well as...
Read more...Review – Product Highlights 2022
Curious about our latest portfolio additions from July to December 2022 and...
Read more...Abraligabra - Reagents and Building Blocks for Chemical Ligation
We can’t get enough of new products and innovations! Read this blog to get...
Read more...ChemMatrix® Discontinued
The ChemMatrix® resin production and distribution was discontinued by its...
Read more...Process Development of SPPS
From mg synthesis of a peptide up to bulk quantities often makes a huge...
Read more...PotM: 1,4-Benzenedimethanethiol (BDMT)
1,4-Benzenedimethanethiol is used as thiol scavenger during solid-phase...
Read more...PotM: Smoc Amino Acids
Herein, we present the Clean Peptide Technology using Smoc Amino Acids...
Read more...Resins for Solid Phase Peptide Synthesis (Part 2)
You want to get an overview about the various resins available at Iris...
Read more...Resins for Solid Phase Peptide Synthesis (Part 1)
You just started working in the field of solid phase (peptide) synthesis and...
Read more...The Dawson Linker
The Dawson Linker and its variants provide access to C-terminal peptide...
Read more...PotM: Towards “Greener” Peptide Synthesis – Alternative Solvents for Loading of 2-CTC and 4-MBH-Br
Replace undesired solvents such as DCM, THF and DMF during the loading of...
Read more...Custom Synthesis Services at Iris Biotech
Iris Biotech is your trusted partner in the world of peptides and all related...
Read more...Sarcosine Building Blocks
Interested in the introduction of Sarcosine (N-methylglycine), e.g. for...
Read more...Review – Product Highlights 2021
Herein, we summarize certain product highlights and innovations, which we...
Read more...2-Chlorotrityl Chloride and 4-Methylbenzhydryl Bromide Resin Loading Using the Mixture of Organic Solvents: A “Greener” Alternative to Dichloromethane and N,N-Dimethylformamide
Common protocols for the loading of 2-CTC and MBH-Br resins presume the...
Read more...Workshop Advances on Cysteine Protecting Groups
You missed our workshop featuring Prof. Dr. Fernando Albericio (University of...
Read more...Hydrazone Resins as Alternative to SEA Resins
Discover the versatile applications of hydrazone resins e.g. for the...
Read more...Measures to Prevent Aspartimide Formation
Aspartimide formation remains one major hurdle during peptide synthesis. Read...
Read more...N-Alkyl Substituted Carboxy Linkers for Peptide Synthesis
Herein, we present Fmoc-protected N-alkyl-substituted carboxy linkers, which...
Read more...Avoiding Racemization: Fmoc-Aaa-MPPAs as Alternatives for Wang Linker during SPPS
Compounds of the shown formula can simply be bound to solid supports via...
Read more...Facilitating the synthesis of hydrophobic peptides and proteins
Cys(Aapam): an Alloc protected Phacm linker as removable side chain...
Read more...Fmoc-MeDbz-OH – Available on Large Scale
Are you using the Fmoc-MeDbz-OH Dawson Linker in large scale on a regular...
Read more...PotM: Asp(CSY) – Tackling Aspartimide Formation
Fmoc-Asp(CSY)-OH – an innovative building block to suppress aspartimide...
Read more...Ramage Linker
An efficient, versatile linker developed for the synthesis of C-terminal...
Read more...Bulky Aspartate Protecting Groups to Avoid Aspartimide Formation
Frustrated by aspartimide formation during peptide synthesis? Iris Biotech...
Read more...New Dawson Linker Derivatives
Interested in the formation of peptide thioesters for Native Chemical...
Read more...Product of the Month: Dde-based Linkers
Placing Dde as one terminal group of a linker and a functional group prone...
Read more...PotM: Peptide Easy Clean (PEC)
Peptide purification after SPPS usually requires time- and solvent-consuming...
Read more...New Warehouse India
Our distribution partner in Mumbai / India, Sumit Biosciences Pvt Ltd.,...
Read more...Product of the Month: Fmoc-L-Cys(Allocam)-OH for 1-Step On-Resin Disulfide Bond Formation
The Allocam protecting group allows for selective deprotection and disulfide...
Read more...Phase change during peptide synthesis. Application of Fmoc-Rink Amide Linker on 2-Chlorotrityl Resin
Abstract: A symposium report. Protected peptides were synthesized using...
Read more...Lysine Dendrons
We now offer a series of Lysine dendrons for chemoselective functionalization...
Read more...The Safety-Catch Acid-Labile (SCAL)-Linker
The SCAL linker offers superior chemical stability and permits a variety of...
Read more...New Iris Kits for the Synthesis of Peptoids and N-Alkylated Peptides
Peptides as pharmaceutical compounds suffer from unfavorable pharmacokinetics...
Read more...Fmoc-Phe-Aca: Fluorescent Internalization Reporter for Cell Penetrating Peptides (CPPs)
The Fmoc-L-Phe-Aca pseudo-dipeptide is a useful reporter group for the...
Read more...Siderophore Building Block: New Hydroxamate-Ornithine for Fmoc/tBu SPPS
Nδ-hydroxy-Nδ-acetyl-ornithine, an important constituent of many...
Read more...Click Chemistry Tools: Propargyl Amino Acids
Click chemistry is a convenient method to chemoselectively functionalize...
Read more...Photo-Linker for Peptide Amides and Acids
Peptide linkers usually are cleaved under acidic conditions or using two-step...
Read more...NEW Hydrazone Resin
A new hydrazone resin enables a convenient way to synthesize peptide...
Read more...4-Methylbenzhydryl-Resins - the Better Wang-Resin alternative
Wang resins are widely used for peptide synthesis. However, certain side...
Read more...Improved Synthesis with Dmb-Glycine Dipeptide Building Blocks
Positions next to Glycine are often reasons for side reactions, as...
Read more...Convenient method of peptide hydrazide synthesis using a new hydrazone resin
Peptide hydrazides can be easily synthesized using a new hydrazone resin,...
Read more...Synthesis of Protected Peptide Amide Fragments with Sieber Resin
Fmoc-Sieber amide resin is an acid-labile carrier for solid phase synthesis...
Read more...The NEW Iris Biotech Catalogue is available now!
In the era of internet a printed edition of a catalogue still has some...
Read more...Preloaded Resins for Synthesis of Peptide Amides
Used for Efficient and Economic Bulk Synthesis of Peptide APIs: A new...
Read more...New TentaGel XV (eXtended swelling Volume)
Resin especially designed for the synthesis of long and difficult peptide...
Read more...N-Fmoc-a-sulfo-b-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy
Abstract: An easy and efficient solid-phase synthesis strategy to obtain...
Read more...Green Advantages of using Phacm for Cystein Protection
PGA (Penicillin G Amidase, Penicillin Acylase, Penicillin Amidohydrolase from...
Read more...Resin-bound mercapto acids: synthesis and application.
Mercapto acids were attached through their thiol group onto 2-chlorotrityl...
Read more...Preparation of the very acid-sensitive Fmoc-Lys(Mtt)-OH. Application in the synthesis of side-chain to side-chain cyclic peptides and oligolysine cores suitable for the solid-phase assembly of MAPs and TASPs
Abstract: N alpha-9-Fluorenylmethoxycarbonyl-N epsilon-4=methyltrityl-lysine,...
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