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News
Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.
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PotM: Furan-Crosslinking and 5HP2O as Maleimide Alternative
Game Changer for Protein Modification: Discover oxidation-induced furan crosslinking and 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones (5HP2Os) as stable alternative to maleimides.
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Workshop: About Furan and a Maleimide Replacement Technology
60-minute online workshop “About Furan and a Maleimide Replacement Technology” on December 4th at 3 pm CET featuring Prof. Dr. Annemieke Madder, Universiteit Gent. Save the date and join us!
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A Fluorescent Probe for “Hard and Soft” Reactive Metabolites
Discover CysGluDan, a new fluorescent probe for the detection of reactive metabolites in drug development, which can detect both "soft" and "hard" nucleophiles.
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Chain Extension: Discover Homo Amino Acids
We expanded our portfolio of Fmoc-protected homo amino acids. Benefit of their unique properties to modulate the stability, hydrophobicity, and biological performance of your peptide!
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HMPO: A pH-Responsive Linker for Targeted Drug Delivery
HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive, 1,6-self-immolative crosslinker derived from the natural product gallic acid. Discover its properties!
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Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.
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Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis
Collect information about the most common side reactions during Fmoc SPPS and how to avoid them! Choose your building blocks and conditions wisely to avoid unnecessary trouble!
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GGFG Motif for ADC Construction
To address both chemical and IP considerations in self-immolating linker applications, we propose shifting from the commonly used Val-Cit-PAB linker to the less explored Gly-Gly-Phe-Gly-formyl motif.
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PotM: Versatile TentaGel® Resins
Discover the diversity of TentaGel® Resins! Read our blog to get more information about our latest product additions and possible applications and find the right resin for your research endeavors!
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About the Evolution of RNA and Peptides
Where does life come from and how can we simulate early earth conditions leading to simple organic molecules such as nucleotides and amino acids, the building blocks of RNA and peptides?
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