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Product Focus
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The Photosensitive MNI Protecting Group
Shining light on 4-methoxy-7-nitroindoline (MNI) photocaged aspartate and glutamate building blocks suitable for Fmoc-SPPS. Liberate the sidechain carboxylic acid by irradiation with UV-light of 365 nm.
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Frequently Asked CliCr® Questions
Improve your click chemistry synthesis with CliCr® - the 7-membered ring strained alkyne TMTHSI is the smallest, most hydrophilic, and highly reactive reagent for copper-free click chemistry.
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New Maillard Products for Peptide Synthesis and Analytics
Benefit of our latest Maillard Reaction Product additions! Use them as reference standard for quality control and food analysis or synthesize modified peptides for research studies.
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A Triazolecarbaldehyde for Selective N-Terminal Protein Modification
Looking for methods to selectively modify your peptide’s N-terminus? Discover triazolecarbaldehydes and benefit of mild reaction conditions, high yields, and compatibility with aqueous media.
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HMPO: A pH-Responsive Linker for Targeted Drug Delivery
HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive, 1,6-self-immolative crosslinker derived from the natural product gallic acid. Discover its properties!
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Hidden Champion – The Tetrahydropyranyl Protective Group
Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.
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GGFG Motif for ADC Construction
To address both chemical and IP considerations in self-immolating linker applications, we propose shifting from the commonly used Val-Cit-PAB linker to the less explored Gly-Gly-Phe-Gly-formyl motif.
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Bioisosteric Argininine Analogs
Same but different! Expand your possibilities for peptide modification and fine-tuning by implementing Nω-carbamoylated arginine building blocks as bioisosteric arginine analogs.
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Bifunctional TentaGel® Resins
Encode beads with unique tags for combinatorial syntheses & screening. Build libraries & identify hits. Discover properties and applications of our novel bifunctional TentaGel® resins.
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Boc versus Fmoc for Solid Phase Peptide Synthesis
Wondering about the difference between Boc and Fmoc chemistry in solid phase peptide synthesis? Don't worry: in this short overview we will guide you through the basics of both strategies.
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