Fmoc-L-Trp(2-CF3)-OH

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-2-trifluoromethyl-L-tryptophane // Synonyms: Fmoc-2-trifluoromethyl-L-tryptophane, (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)-1H-indol-3-yl)propanoic acid, Fmoc-Trp(2-CF3)-OH

  • Product code:FAA8290
  • CAS No.:2576508-09-1
  • Formula:C27H21F3N2O4
  • Molecular weight:494.47 g/mol

from $500.00

Grouped product items
Qty Packing unit Price SKU Availability
250 mg
$500.00
FAA8290.0250
<10 business days
1 g
$1,500.00
FAA8290.0001
<10 business days
references

NMR-Solution Structures and Affinities for the Human Somatostatin G-Protein-Coupled Receptors hsst1-5 of CF3 Derivatives of Sandostatin® (Octreotide); D. Seebach, H. Widmer, S. Capone, R. Ernst, T. Bremi, I. Kieltsch, A. Togni, D. Monna, D. Langenegger and D. Hoyer; Helvetica Chimica Acta 2009; 92: 2577-2586. https://doi.org/10.1002/hlca.200900279

Selective Radical Trifluoromethylation of Native Residues in Proteins; M. Imiolek, G. Karunanithy, W. L. Ng, A. J. Baldwin, V. Gouverneur and B. G. Davis; J Am Chem Soc 2018; 140: 1568-1571. https://doi.org/10.1021/jacs.7b10230

Selective Photoredox Trifluoromethylation of Tryptophan-Containing Peptides; B. Ding, Y. Weng, Y. Liu, C. Song, L. Yin, J. Yuan, Y. Ren, A. Lei and C.-W. Chiang; European Journal of Organic Chemistry 2019; 2019: 7596-7605. https://doi.org/10.1002/ejoc.201901572

(18)F-Trifluoromethanesulfinate Enables Direct C-H (18)F-Trifluoromethylation of Native Aromatic Residues in Peptides; C. W. Kee, O. Tack, F. Guibbal, T. C. Wilson, P. G. Isenegger, M. Imiolek, S. Verhoog, M. Tilby, G. Boscutti, S. Ashworth, J. Chupin, R. Kashani, A. W. J. Poh, J. K. Sosabowski, S. Macholl, C. Plisson, B. Cornelissen, M. C. Willis, J. Passchier, B. G. Davis and V. Gouverneur; J Am Chem Soc 2020; 142: 1180-1185. https://doi.org/10.1021/jacs.9b11709

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