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H-L-Arg-AMC*2HCl
Chemical name: L-Arginine 7-amido-4-methylcoumarin dihydrochloride // Synonyms: H-Arg-AMC*2HCl
- Product code:HAA7630
- CAS No.:113712-08-6
- Storage temperature:2-8°C
- Formula:C16H21N5O3*2HCl
- Molecular weight:331.37*72.90 g/mol
- Purity :min. 99%
- Enantiomeric Purity:min. 99,7%
from $93.75
description
Excellent sensitive fluorogenic substrate for the quantitative determination of cathepsin H activity. Also useful as a substrate for aminopeptidase B, aminopeptidase in common, pepN, pepC, Trypsin.
Yields a blue fluorescent solution upon cleavage.
references
Barrett A.J., Fluorimetric assays for cathepsin B and cathepsin H with methylcoumarylamide substrates. Biochem. J. 1980, 187, 909-12.
Barrett A.J., Kirschke H., Cathepsin B, Cathepsin H, and Cathepsin L. Methods Enzymol. 1981, 80, 535-61.
Sanz Y., Toldrá F., Purification and Characterization of an Arginine Aminopeptidase from Lactobacillus sakei. Appl. Env. Microbiol. 2002, 68, 1980-7.
Schwartz W.N., Barrett A.J., Human Cathepsin H. Biochem. J. 1980, 191, 487-97.
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