Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
USD
Quick contact
Please send me more information about
Leupeptin Hemisulfate
Chemical name: N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt // Synonyms: Acetyl-Leu-Leu-Arg-al
- Product code:LS-3900
- CAS No.:103476-89-7
- Formula:C20H38N6O4 * 1/2H2SO4
- Storage temperature:-20°C
- Molecular weight:475.59 g/mol
from Please inquire
description
A potent, reversible inhibitor of serine and cysteine proteases that shows little to no inhibitory activity against pepsin, cathepsins A and D and alpha-chymotrypsin.
references
Active and inactive forms of the transition-state analog protease inhibitor leupeptin: explanation of the observed slow binding of leupeptin to cathepsin B and papain; R. M. Schultz, P. Varma-Nelson, R. Ortiz, K. A. Kozlowski, A. T. Orawski, P. Pagast and A. Frankfater; J Biol Chem 1989; 264: 1497-507.
Inhibition of thrombin-induced platelet activation by leupeptin. Implications for the participation of calpain in the initiation of platelet activation; L. F. Brass and S. J. Shattil; J Biol Chem 1988; 263: 5210-6.
Successful treatment of murine muscular dystrophy with the proteinase inhibitor leupeptin; J. H. Sher, A. Stracher, S. A. Shafiq and J. Hardy-Stashin; Proc Natl Acad Sci U S A 1981; 78: 7742-4.
Letter: A thermolysin inhibitor produced by Actinomycetes: phospholamidon; H. Suda, T. Aoyagi, T. Takeuchi and H. Umezawa; The Journal of antibiotics 1973; 26: 621-3.
Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes; M. Hozumi, M. Ogawa, T. Sugimura, T. Takeuchi and H. Umezawa; Cancer Res 1972; 32: 1725-8.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
We found other products you might like!
