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Biotin-mal
Chemical name: N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide // Synonyms: Biotin-maleimide
- Product code:LS-4220
- CAS No.:139554-72-6
- Formula:C16H22N4O4S
- Molecular weight:366.44 g/mol
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description
This biotin derivative bears a terminal maleimide moiety. It can be used to prepare various biotinylated conjugates. Biotin can be subsequently detected e.g. via streptavidin or avidin. Maleimides react preferentially with free thiols under the formation of thioethers.
references
The influence of structural gradients in large pore organosilica materials on the capabilities for hosting cellular communities; H. Bronner, A.-K. Holzer, A. Finke, M. Kunkel, A. Marx, M. Leist, S. Polarz; RSC Adv. 2020; 10: 17327-17335. https://doi.org/10.1039/D0RA00927J.
Molecular recognition moiety and its target biomolecule interact in switching enzyme activity; Y. Oshiba, T. Tamaki, H. Ohashi, H. Hirakawa, S. Yamaguchi, T. Najamune, T. Yamaguchi; J. Biosci. Bioeng. 2013; 115(6): 639-644. https://doi.org/10.1016/j.jbiosc.2012.12.019.
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