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Fmoc-NH-SS-Bzl-OH
Chemical name: 4-((2-((9-Fluorenylmethyloxycarbonyl)amino)ethyl)disulfaneyl)benzylalcohol // Synonyms: (9H-fluoren-9-yl)methyl (2-((4-(hydroxymethyl)phenyl)disulfaneyl)ethyl)carbamate
- Product code:RL-3580
- CAS No.:2064282-26-2
- Formula:C24H23NO3S2
- Storage temperature:-20°C
- Molecular weight:437.57 g/mol
from $312.50
description
Fmoc-protected self-immolative linker for traceless bioconjugation.
references
Disulfide-Based Self-Immolative Linkers and Functional Bioconjugates for Biological Applications; Z. Deng, J. Hu and S. Liu; Macromol Rapid Commun 2020; 41: e1900531. https://doi.org/10.1002/marc.201900531
Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates; Z. Deng, S. Yuan, R. X. Xu, H. Liang and S. Liu; Angew Chem Int Ed Engl 2018; 57: 8896-8900. https://doi.org/10.1002/anie.201802909
Intracellular Delivery of Native Proteins Facilitated by Cell-Penetrating Poly(disulfide)s; L. Qian, J. Fu, P. Yuan, S. Du, W. Huang, L. Li and S. Q. Yao; Angew Chem Int Ed Engl 2018; 57: 1532-1536. https://doi.org/10.1002/anie.201711651
Thiolytically cleavable dithiobenzyl urethane-linked polymer-protein conjugates as macromolecular prodrugs: reversible PEGylation of proteins; S. Zalipsky, N. Mullah, C. Engbers, M. U. Hutchins and R. Kiwan; Bioconjug Chem 2007; 18: 1869-78. https://doi.org/10.1021/bc7001902
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