Search results for: 'thr'

New Maillard Products for Peptide Synthesis and Analytics

Benefit of our latest Maillard Reaction Product additions! Use them as...

Chain Extension: Discover Homo Amino Acids

We expanded our portfolio of Fmoc-protected homo amino acids. Benefit of...

HMPO: A pH-Responsive Linker for Targeted Drug Delivery

HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive,...

Hidden Champion – The Tetrahydropyranyl Protective Group

Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and...

Common Side Reactions in Fmoc Solid-Phase Peptide Synthesis

Collect information about the most common side reactions during Fmoc SPPS and...

Bioisosteric Argininine Analogs

Same but different! Expand your possibilities for peptide modification and...

Protecting Groups in SPPS

Mix & Match. Discover typically employed protecting groups used to...

Latest Products 2024 (Part 1)

What’s new? Don’t miss innovative building blocks and latest technologies...

Deprotection and Coupling in SPPS

Get the most out of your synthesis! Monitor your deprotection and coupling...

Bifunctional TentaGel® Resins

Encode beads with unique tags for combinatorial syntheses & screening....

Boc versus Fmoc for Solid Phase Peptide Synthesis

Wondering about the difference between Boc and Fmoc chemistry in solid phase...

“Power On” – Activity Control by Photocaging

Discover photocages – photosensitive protecting groups that are removed by...

2-Cyanopyridines for Click-Like Reactions

Have an additional ace up your sleeve for selective and efficient peptide...

Workshop : Fluorogenic Amino Acids for SPPS

You missed our workshop featuring Dr. Fabio de Moliner & Prof. Dr. Marc...

Phenylboronate Amino Acid Building Blocks

Boron is not boring at all! Today, we'll delve deeper into the exciting world...

Phenylisopropylester (OPP) as Carboxy Protecting Group

Explore phenylisopropylesters (OPP/OPis) as carboxy protecting groups....

PotM: Blockbuster Building Blocks

Are you keen on developing novel billion-dollar-selling peptide API...

Special Deal: Amino Acid Bundle

Our special Christmas offer is still valid! Get our standard L-amino acid...

Review – Product Highlights 2023

Curious about the highlights of our 2023 portfolio additions? Discover...

Workshop on Click Chemistry in the Context of Automated Peptide Synthesis

You missed our workshop featuring Dr. Quibria Guthrie (CEM Corporation)? Any...

Combination Therapy & Linkerology®

Discover possibilities to fight chronic pain diseases by employing linker...

Special Christmas Offer!

Do not miss our special Christmas offer starting on December 1st!

Glycosylated Asparagine Building Blocks for SPPS

Add glycans to your proteins with our ready-to-use Fmoc asparagine building...

PotM: Small-sized, neutral fluorogenic amino acids suitable for SPPS

Discover our small-sized, neutral Fmoc-protected nitrobenzoselenadiazole- and...

PotM: Next Generation Lysine Side Chain Protecting Groups

Sick of Lysine side chain protecting groups jumping around, yielding...

Linkerology® on Metal & Ore Surfaces

A heart of gold! Metals and ores - see here how their surfaces can be...

Process Development – From Discovery to Scale-up

Ongoing research efforts lead to the discovery of innovative building blocks...

Selective Lysine Labeling with Squaric Acid

Keeping control! PEGylating reagents with a squaric acid ethyl ester react...

Cell-Free Bioengineering & Linkerology®

Bioengineering in combination with Linkerology®. Check out the unique...

PotM: TCEP as Versatile Reducing Agent

TCEP is an effective reductant for disulfide bonds and a versatile reagent...

Conjugating Natural Products (3)

The potential of natural products of daily life, such as 6-shogaol from...

Functionalization of Carbon Materials by Linker Attachment

Allotropes of carbon show distinct characteristics in structure and e.g....

Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation

Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so...

PotM: Safety Catch - Orthogonally Protected Amino Acids

Add a new dimension of orthogonality to your peptide synthesis by using...

Workshop Innovations in Click Chemistry

You missed our workshop featuring Prof. Rob Liskamp (Cristal Therapeutics,...

CliCr® - a Reactive and Soluble Bioorthogonal Click Reagent

Building blocks with a strained triple bond do not require copper catalysis...

PotM: Limited Offer - Polysarcosine Bundles

From beginning of May until end of July 2023 we offer special polysarcosine...

Conjugating Natural Products (1)

From evolution to solution - natural products are an infinite source of...

PotM: Functionalized Dextrans

Our monofunctionalized dextrans are enriching the toolbox of polymer...

Coupling Reagents

Coupling Reagents are required for the formation of an amide or ester bond....

PotM: Perfluorobiphenyl Building Blocks for Site-Selective Cysteine Conjugation

Herein, we present functionalized perfluorobiphenyl building blocks which can...

Amino-PEG-Acids

PEGs are being used as spacers, as hydrophilic decoration, and building...

PotM: Argpyrimidine Building Block for SPPS

Argpyrimidine is the result of a Maillard Reaction-like nonenzymatic...

Choose your Taste – Functionalized Halo/Snap/Clip Substrates

The HaloTag®, SNAP-Tag® and CLIP-TagTM represent versatile tools for the...

Temporary Activity Masking via Self-Immolative Linkage

(Bi)functional dioxoborolane and disulfide-based self-immolative linkers –...

Acylation Efficiencies on Ser and Thr Pseudoproline Monomers

In two joint studies together with Prof. F. Albericio we investigated the...

Incorporation of pseudoproline monomer (Fmoc-Thr[ψMe,Mepro]–OH) facilitates efficient solid-phase synthesis of difficult peptides

Herein we investigate the incorporation of the Fmoc-Thr-pseudoproline monomer...

PotM: His Tags for the Chemical Modification of Peptides

Jensen et al. developed two methods that use poly-His sequences to direct the...

DTT and Spermidine for RNA Buffers and Vaccine Production

See how our “mRNA grade” DTT and Spermidine can support also your nucleic...

ChemMatrix® Discontinued

The ChemMatrix® resin production and distribution was discontinued by its...

PotM: Fmoc-Ser(Msbh)-OH

You are working on complex peptides and are looking for a new level of...

Process Development of SPPS

From mg synthesis of a peptide up to bulk quantities often makes a huge...

Solid-Phase Peptide Synthesis Using a Four-Dimensional (Safety-Catch) Protecting Group Scheme

As the molecular diversity of cyclic and branched peptides becomes more and...

Resins for Solid Phase Peptide Synthesis (Part 2)

You want to get an overview about the various resins available at Iris...

Resins for Solid Phase Peptide Synthesis (Part 1)

You just started working in the field of solid phase (peptide) synthesis and...

The Dawson Linker

The Dawson Linker and its variants provide access to C-terminal peptide...

pH-Sensitive Self-Immolative Linkers

Are you active in the field of antibody drug conjugates? Click here to find...

Photoswitches

Photoswitches grant the ability to modulate the function of a molecule by...

Workshop Polymer Therapeutics for Improved Drug Delivery

You missed our workshop featuring Prof. María Jesus Vicent Docón (Head of...

Dyes and Fluorescent Labels at Iris Biotech

Dyes and fluorescent labels are an invaluable tool for diagnostics, medical...

Peptide Easy Clean – Because Time Matters

We want to support you in the development of next generation peptide...

PotM: Proteolysis Targeting Chimeras (PROTACs®)

Drug the undruggable – click here to get more information about the use of...

Workshop Complex peptide manufacturing made easy with PEC

You missed our workshop featuring Dr. Nadja Berger and Dr. Manoj Kumar...

PotM: Substrates for Fusion (Halo/Snap/Clip)-Tagged Proteins

Discover our selection of substrates for Halo-, Snap-, and Clip-tagged...

Review – Product Highlights 2021

Herein, we summarize certain product highlights and innovations, which we...

Workshop Advances on Cysteine Protecting Groups

You missed our workshop featuring Prof. Dr. Fernando Albericio (University of...

Conformationally Constrained Amino Acid Derivatives

Herein we present a series of alpha,alpha-cycle-disubstituted amino acid...

N-Methylation of Amino-PEG-Acids

Herein we are reporting on the linker stability of amino-PEG-acids achieved...

Pseudoproline Monomers

Typically known and employed as preformed dipeptides, we are presenting...

PotM: Polysarcosines for Drug Delivery

Polysarcosines (PSars) – a true alternative to polyethyleneglycols (PEGs) -...

Hydrazone Resins as Alternative to SEA Resins

Discover the versatile applications of hydrazone resins e.g. for the...

PotM: Seleno Amino Acids

Selenocysteine (Sec) plays a crucial role for various biological processes,...

Protease Stable Ile/Leu Surrogates

Herein we are presenting 2-(Fmoc-amino)-3,3-diMe-pent-4-enoic acid (FAA5040),...

Measures to Prevent Aspartimide Formation

Aspartimide formation remains one major hurdle during peptide synthesis. Read...

PotM: Functionalized Biotinylation Reagents

Iris Biotech offers a variety of (functionalized) biotin and desthiobiotin...

N-Alkyl Substituted Carboxy Linkers for Peptide Synthesis

Herein, we present Fmoc-protected N-alkyl-substituted carboxy linkers, which...

PotM: Methanoprolines and Dimethylprolines - Constraining the Conformation of Peptides

Interested in structure-activity studies of your Proline-containing peptide...

About the Advantages of Pseudoproline Dipeptides

Serine- and Threonine-derived oxazolidines as well as Cysteine-derived...

Thiol- and Amine Reactive Crosslinkers

Iris Biotech offers hetero-bifunctional crosslinkers bearing an...

PotM: Pyridyldithiols as Precursors for Disulfide-Based (Self-Immolative) Linkers

Read on to find out more about Iris Biotech’s Linkerology® portfolio...

Fmoc-L-Cys(Palm)-OH – A S-palmitoylated Cysteine building block

Interested in studying the effect of palmitoylation on your peptide’s...

Facilitating the synthesis of hydrophobic peptides and proteins

Cys(Aapam): an Alloc protected Phacm linker as removable side chain...

Fmoc-MeDbz-OH – Available on Large Scale

Are you using the Fmoc-MeDbz-OH Dawson Linker in large scale on a regular...

DACNs for Strain-Promoted Azide-Alkyne Cycloadditions (SPAAC)

Herein we present substituted diazacyclononynes (DACNs) as versatile tools...

Adamantyls are a Chemist’s Best Friend

The highly lipophilic, bulky adamantyl motif is a promising and validated...

Ramage Linker

An efficient, versatile linker developed for the synthesis of C-terminal...

8th Indian Peptide Symposium

March 24-26th, 2021

PotM: SIT – A New Cysteine Protecting Group

The new disulfide-based protecting group sec-isoamyl mercaptan (SIT) is fully...

Cyclopropyl Modification

Cyclopropanes represent important design elements in medicinal chemistry and...

Workshop on Belyntic's Peptide Easy Clean (PEC)

March 4, 2021

Trimethyl Locks

The sterical interference of three closely positioned methyl groups favors...

New Dawson Linker Derivatives

Interested in the formation of peptide thioesters for Native Chemical...

Amino-Methylcoumarins as Fluorescent Labels

Enzymatically-activatable probes based on 7-amino-4-methylcoumarin (AMC)...

Product of the Month: Fluorinated Amino Acids

One approach for the design of bioactive peptides with improved...

Thiol-reactive Linkers for ADCs

The thiosuccinimide linkage is a prominent connective motif resulting from...

Product of the Month: Fluorescent SARS-CoV-2 Protease Substrates

Mpro is a key enzyme of coronaviruses (coronaviridae) and thus an attractive...

Deamino- and Decarboxy-Histidine Derivatives

Interested in histidine derivatives? Iris Biotech provides a selection of...

Fighting SARS-CoV-2

Fighting COVID-19 by modifying essential viral proteins via glycation through...

Product of the Month: Imatinib And Other Linked Kinase Inhibitor Analogues

Iris Biotech offers various linked kinase inhibitors including analogues of...

Nitrodibenzofuran (NDBF) based Photocleavable Protecting Groups

Nitrodibenzofuran (NDBF) is a photocleavable side chain protecting group that...

Product Focus: Next Generation Phosphoamino Acid Analogs

Iris Biotech presents the next-generation of hydrolysis-stable...

Product Focus: Arginine Derivatives

Looking to optimize or functionalize your peptide? Explore our ever-growing...

Product Focus: TT-232, a Potent Somatostatin Analogue

Amongst various somatostatin analogues, the pentacyclic heptapeptide TT-232...

Identification and Quantification of Maillard RPs

Find out which Maillard Reaction Products from Iris Biotech were used in the...

Peptide Easy Clean (PEC): now distributed in India

Now in India available: the Belyntic Kits Peptide Easy Clean (PEC)

Alkyne Amino Acids for Click Chemistry and other Conjugations:

Alkyne amino acids allow for Click conjugations and other types of chemistry....

Product of the Month: cyclo-Arg-Gly-Asp (RGD) Peptides

The integrin receptor interacting RGD sequence and related peptides act as...

Product of the Month: “Cleland’s Reagent” Dithiothreitol (DTT)

DTT is a powerful yet mild reducing agent. Based on your demand we can offer...

PotM: Peptide Easy Clean (PEC)

Peptide purification after SPPS usually requires time- and solvent-consuming...

Lipidated Amino Acids

The tremendous success of Liraglutide and Semaglutide has moved amino acids...

4th GFPP Chemical Ligation Meeting

27 - 29 January 2020

Cleavable Bifunctional Biotin-Linkers

Biotinylation of proteins and their purification via Streptavidin beads is a...

Unsere neuen Mitarbeiterinnen - Our new trainees

MedChem 2019

22 November 2019

Product of the Month: Fmoc-L-Cys(Allocam)-OH for 1-Step On-Resin Disulfide Bond Formation

The Allocam protecting group allows for selective deprotection and disulfide...

BioJapan 2019

9 - 11 October 2019

6th Annual Peptides Congress

24 - 25 April 2019

Membrane-Impermeant Biotin Tyramide

Methods for proteomic mapping of cellular organelles or subdomains that avoid...

Fmoc-L-Lys(Nvoc)-OH

o-Nitroveratryloxycarbonyl (Nvoc) is a photocleavable side chain protecting...

CPHI worldwide

09 – 11 October 2018

BioJapan 2018

10 – 12 October 2018

RICT 2018 - Interfacing Chemical Biology and Drug Discovery

July 4-6, 2018

A Cyclo-RGD Peptide for the Preparation of Tumor Mimics

The 2D monolayer cell culture model is widely applied for drug screening....

Hydrolysis-Stable Mimics of Phosphorylated Amino Acids (Ser, Thr and Tyr)

Phosphorylation of serine, threonine and tyrosine is counted among the most...

5th Annual Peptides Congress

16-17 April 2018

Polyarginine

Polyarginines are well known for their ability to enhance cell penetration.

Fmoc-L-Cys(Propargyl)-OH

This alkyne-functionalized cysteine building block can be incorporated into...

Proline Scaffold

One role of proline in proteins is that a β-turn of a peptide chain is being...

RICT 2017 - Drug Discovery & Selection

5 - 7 July 2017

4th Annual Peptide Congress

24 - 25/04/2017

2nd Generation Click Chemistry

Recombinant Incorporation of Amino Acids into Proteins

Mutant or modified aminoacyl tRNA synthetases (aaRS) have been used to charge...

Peptide Structure Stabilization by Click Chemistry

As Boc and Fmoc protected derivatives of both azido and alkyne amino acids...

Carbohydrates for Click Chemistry

Protein and lipid glycosilation is a life-governing and omnipresent process....

Click Chemistry in DNA Synthesis

Click Chemistry in DNA Synthesis - Applications and Procedures in DNA Synthesis

Standard approaches

Diethyl-acetamidomalonate Route: The probably most widely used first approach...

α-Methyl and β,β-dimethyl amino acids

α-Methyl and alkyl-amino acids can be produced by a number of platforms,...

Specific Linkers

The variations for linkers are endless, as in our catalogue program already...

Polydispersity of Polymer Carriers

The polymers in this context are a polymeric linear structures with n...

Comparison of Carriers for Polymer Therapeutics

The polymers in this context are a polymeric linear structures with n...

Poly(Glutamic Acid) as Versatile Biodegradable Drug Carrier

Polyglutamates are well known to be highly biocompatible, biodegradable and...

Polysarcosine – a True Alternative to PEG

Potential alternatives to PEGs, polypeptoids in general and polysarcosine...

Poly(Ethylene Glycol) – the Pioneer in Polymer Therapeutics

PEGs show a spectrum of unique physical and chemical properties, which have...

Lipoamide-PEGs Confer Extra Strong Binding

Nanotechnology and nanobiotechnology using gold or silver particles, quantum...

Polymers Enlarge the Potential of Biopharmaceuticals

The Biopharmaceuticals market, estimated at US$ 200 billion globally in 2013...

Pharmacological Effects of Polymer Therapeutics

Small drug molecules and also large biomolecules like proteins or antibodies...

A Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Model for Predicting the Enantioselectivity of Candida antarctica Lipase B

Lysine Dendrons

We now offer a series of Lysine dendrons for chemoselective functionalization...

Coupling Reagents for Peptide Chemistry

In this news section, we highlight three useful coupling reagents for peptide...

PEG-Conjugates of Folic Acid and Cholesterol

Conjugates of PEG and folic acid or cholesterol, respectively, combine the...

CPhI worldwide

4-6 October 2016Fira de Barcelona Gran Via, BarcelonaSpain

New Iris Kits for the Synthesis of Peptoids and N-Alkylated Peptides

Peptides as pharmaceutical compounds suffer from unfavorable pharmacokinetics...

Msbh, a Safety Catch Cysteine Protecting Group for the Synthesis of Cyclic Peptides

The regioselective formation of multiple disulfide bonds is often a synthetic...

Furyl-Alanine: A Novel Photo-Click Amino Acid

2-Furyl-alanine can be incorporated into peptides via SPPS or by using...

AUSBIOTECH 2015

October 7 to 9 2015 Melbourne, Victoria,...

BioJapan 2015

October 14 to 16, 2015Pacifico Yokohama,...

The 6th World ADC Conference

October 19 to 21, 2015Sheraton San Diego Hotel & Marina, San Diego, CA,...

New: Guanidino-Glycine

Visit our Glycine section and find a series of amino acid derivatives, where...

New: Oligo Glycine – Linker

Oligo-glycines are either flexible linkers or form well defined rigid...

NGlyO – for beta sheet formation

Surprising behavior of NXO-peptides. It is a significant property of peptides...

Peptoids - Peptide Backbone Derivatisation

Alkylating the Nitrogen of an amide bond results in peptoid structures,...

Peptide Solutions Appointed as Distributor for Iris Biotech for all North American Sales

We at Iris Biotech, are pleased to announce that we have entered into an...

New Statin Analogues: Super-Threonine Derivatives

A set of new statin analogues, so called Super-Threonines, is available...

2nd NovAliX Conference Biophysics in Drug Discovery 2015

June 9th - 12th, 2015Palais UniversitaireStrasbourg, France The use of...

New: Cysteine-Pseudoproline

Pseudoprolines derived from Serine and Threonine have developed to standard...

10th Status Seminar Chemical Biology

January 20th-21st, 2015Dechema-HausFrankfurt, Germany   The 10th Status...

Stable Conjugation with Thiols

Maleimide (MAL) reacts rather specific with free thiol groups and forms...

Polar Amino Acids for Increased Solubilization

alpha-Sulfo-beta-Alanine has been used to couple to hydrophobic molecules and...

MedChem 2014

November 21st, 2014Llyod Conference Room, UCB PharmaBraine-L'Alleud, Belgium...

Boulder Peptide Symposium 2014

September 22nd - 24th, 2014St. Julien Hotel & SpaBoulder, COUSA ABOUT THE...

Custom Synthesis of Alkyne Amino Acids Analogues for Click Conjugation

1,4-substituted 1,2,3-triazole are isosteric to peptide bonds and result in...

Custom Synthesis of Click-able compounds for Cu-free Click Conjugation

The presence of catalytic copper, limits the in vivo application of the Click...

Life Science Baltics 2014

September 10th - 12th, 2014LITEXPO, VilniusVilnius, Lithuania Life Sciences...

Preloaded Resins for Synthesis of Peptide Amides

Used for Efficient and Economic Bulk Synthesis of Peptide APIs: A new...

New: dPEG-Phospholipids for superior liposomes

Novel liposomes built of dPEG-Phospholipids with defined PEG chain length...

RICT 2014 - 50th International Conference on Medicinal Chemistry

July 2nd - 4th, 2014Rouen’s Law FacultyRouen, Normandy, France The...

14th Naples Workshop on Bioactive Peptides

June 12th - 14th, 2014Centro Congressi of University of Naples "Frederico...

10th International Symposium on Polymer Therapeutics

May 19th - 21th, 2014Centro de Investigación Príncipe...

Bis-Mal-Lysine

Bis Thiol & Amine reactive PEGylated Cross-Linker which has been used for...

Phthalimidooxy PEG-based cross linkers

Phthalimidooxy PEG-based cross linkers form stable oximes with aldehydes,...

MiDye is YOUR Dye!

Superior Performance at a Sensational Price! Available as –COOH, -NHS,...

8th Status Seminar Chemical Biology

January 22nd - 23rd, 2013DECHEMA-HausFrankfurt am Main, Germany The...

Recap China Hi-Tech Fair 2013

Cfm Oskar Tropitzsch and Iris Biotech GmbH attended the China Hi-Tech-Fair...

Ellmans Reagent

DTNB, frequently called Ellman’s Reagent, used as reagent for determination...

CPhI worldwide

October 22th-24th, 2013Frankfurt/Main, Germany CPhI Worldwide 2013...

Product of the Month: Fmoc-L-Cys(Dpm)-OH

Any amino acid can be functionalized on the N-terminus with oxalic acid and...

CPhI worldwide

October 9th-11th, 2012Feria de Madrid, Spain CPhI Worldwide 2012 is...

32nd European Peptide Symposium

September 2nd - 7th, 2012Athens, GreeceMegaron Conference Centre   With...

4th International Conference on Drug Discovery and Therapy

February 12th - 15th, 2012Dubai, UAE This unique international...

Available Bulk

Our portfolio currently contains over 5500 products. Many of them – in...

Alpha-Sulfo-beta-Alanine

alpha-Sulfo-beta-Alanine has been used to couple to hydrophobic labels like...

4-Azido-L-homoalanine

H-L-Aha-OH*HClH-L-Dab(N3)-OH 4-Azido-L-homoalanine(S)-2-Amino-4-azidobutanoic...

DTT (Cleland's Reagent)

Cleland's reagent, also known as dithiothreitol or DTT is a water soluble...

Green Advantages of using Phacm for Cystein Protection

PGA (Penicillin G Amidase, Penicillin Acylase, Penicillin Amidohydrolase from...

Dendron Building Blocks for Click Chemistry

Dendrimers offer a new possibility to derivatize small molecules, surfaces or...

Shorter Arginine homologues to stabilize peptides towards tryptic digestion

Abstract: Trypsin digests peptides at the position of arginine. Because...

Resin-bound mercapto acids: synthesis and application.

Mercapto acids were attached through their thiol group onto 2-chlorotrityl...

Preparation of the very acid-sensitive Fmoc-Lys(Mtt)-OH. Application in the synthesis of side-chain to side-chain cyclic peptides and oligolysine cores suitable for the solid-phase assembly of MAPs and TASPs

Abstract: N alpha-9-Fluorenylmethoxycarbonyl-N epsilon-4=methyltrityl-lysine,...