Welcome to Iris Biotech
For better service please confirm your country and language we detected.
Currency
EUR
Quick contact
Please send me more information about
Smoc-L-Cys(Trt)-OH
Chemical name: N-(((2,7-disulfo-9H-fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-cysteine potassium salt // Synonyms: potassium (R)-9-((((1-carboxy-2-(tritylthio)ethyl)carbamoyl)oxy)methyl)-9H-fluorene-2,7-disulfonate, Smoc-Cys(Trt)-OH
- Product code:SAA1110
- CAS No.:2442552-68-1
- Formula:C37H29K2NO10S3
- Storage temperature:2-8°C
- Molecular weight:822.01 g/mol
from €70.00
description
Building blocks for aqueous solid-phase peptide synthesis (ASPPS). The 2,7-disulfo-9-fluorenylmethoxycarbonyl (Smoc) protecting group allows peptide synthesis using water instead of organic solvents – finally combining sustainability with cost optimization. The building blocks possess significant stability in basic aqueous solutions, but are easily losing their amino terminal protection upon mild treatment with particular water-soluble bases, e.g. NaOH, NH3, piperazine or ethanolamine. For ASPPS, a water-compatible resin, e.g. Tentagel, ChemMatrix, is required.
references
Method for peptide synthesis and apparatus for carrying out a method for solid phase synthesis of peptides; S. Knauer, T. M. L. Roese, O. Avrutina, H. Kolmar, C. Uth; 2016, WO 2016 050764.
Sustainable Peptide Synthesis Enabled by a Transient Protecting Group; S. Knauer, N. Koch, C. Uth, R. Meusinger, O. Avrutina, H. Kolmar; Angew. Chem. Int. Ed. 2020; 59(31): 12984-12990. https://doi.org/10.1002/anie.202003676.
Improved method for preparing peptides; S. Knauer; WO 2019 101939.
Method for preparing peptides; S. Knauer; WO 2019 101940.
* Disclaimer
We refer to our general terms and conditions.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
All information contained in our webshop is compiled to the best of our knowledge.
Prices and product availability are subject to change and require reconfirmation. Please contact us for further information.
Do you need further information about this product?
get in contact
Brochures & Flyers
