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Boc-3,3-dmP-OH (S)
Chemical name: N-alpha-t-Butyloxycarbonyl-beta,beta-dimethyl-L-proline // Synonyms: Boc-beta,beta-diMe-L-Pro-OH, (S)-Boc-3,3-dimethyl-proline, (S)-Boc-3,3-dimethyl-pyrrolidine-2-carboxylic acid, (S)-1-(tert-butoxycarbonyl)-3,3-dimethylpyrrolidine-2-carboxylic acid
- Product code:BAA2870
- CAS No.:174060-98-1
- Formula:C12H21NO4
- Storage temperature:2-8°C
- Molecular weight:243.30 g/mol
from $281.25
description
beta,beta-Dimethylation of amino acids stabilizes appropriate peptides towards digestion by proteases.
references
Benzyl 2-Cyano-3,3-Dimethyl-1-pyrrolidinecarboxylate, a Versatile Intermediate for the Synthesis of 3,3-Dimethylproline Derivatives; Jesus R.Medina, Charles W. Blackledge, Karl F. Erhard, Jeffrey M. Axten, and William H. Miller; J. Org. Chem. 2008; 73: 3946-3949. DOI: 10.1021/jo7027163.
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