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Fmoc-L-Pyrraline(TBS)-OH
Chemical name: N-alpha-(9-Fluorenylmethoxycarbonyl)-6-(2-((t-butyldimethylsilyloxy)methyl)-5-formyl-1H-pyrrol-1-yl)-L-norleucine // Synonyms: N-alpha-Fmoc-O-(t-butyldimethylsilyl)-L-pyrraline, (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-(2-((t-butyldimethylsilyloxy)methyl)-5-formyl-1H-pyrrol-1-yl)hexanoic acid,Fmoc-Pyrraline(TBS)-OH
- Product code:FAA7520
- CAS No.:1404451-31-5
- Formula:C33H42N2O6Si
- Molecular weight:590.78 g/mol
from $250.00
description
Pyrraline is an advanced glycation end product (AGE) or a Maillard reaction product (MRP). This pyrraline derivative can be used in standard Fmoc/tBu peptide synthesis protocols, in order to yield peptides with increased proteolytic stability.
references
Chemical Synthesis of Peptides Containing Site-Specific Advanced Glycation Endproducts; H. Kaur, M. Kamalov and M. A. Brimble; Acc Chem Res 2016; 49: 2199-2208. https://doi.org/10.1021/acs.accounts.6b00366
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