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GLAP
Chemical name: (S)-1-(5-amino-5-carboxypentyl)-3-hydroxy-5-(hydroxymethyl) pyridinium trifluoroacetic acid
- Product code:HAA3975
- CAS No.:889659-45-4
- Formula:C12H19N2O4+
- Storage temperature:-20°C
- Molecular weight:255.29 g/mol
from $225.00
description
An advanced glycation end product formed by glyceraldehyde-related glycation. This compound is reported to be cytotoxic.
references
DNA-aptamers raised against AGEs as a blocker of various aging-related disorders; S.-I. Yamagishi, K. Taguchi, K. Fukami; Glycoconj J 2016; 33: 683–690. https://doi.org/10.1007/s10719-016-9682-2
Formation Mechanisms of Melanoidins and Fluorescent Pyridinium Compounds as Advanced Glycation End Products; F. Hayase, T. Usui, Y. Ono, Y. Shirahashi; T. Machida, T. Ito, N. Nashitani, K. Shimohira, H. Watanabe; Ann. N.Y. Acad. Sci. 2008; 1126(1): 53-58. https://doi.org/10.1196/annals.1433.009
Detection and Determination of Glyceraldehyde-Derived Pyridinium-Type Advanced Glycation End Product in Streptozotocin-Induced Diabetic Rats; T. Usui, K. Shimohira, H. Watanabe, F. Hayase; Biosci. Biotechnol. Biochem. 2007; 71(2): 442-448. https://doi.org/10.1271/bbb.60497
Chemistry and Biological Effects of Melanoidins and Glyceraldehyde-Derived Pyridinium as Advanced Glycation End Products; F. Hayase, T. Usui, K. Nishiyama, S. Sasaki, Y. Shirahashi, N. Tsuchiya, N. Numata, H. Watanabe; Ann. N.Y. Acad. Sci. 2005; 1043(1): 104-110. https://doi.org/10.1196/annals.1333.013
Cytotoxicity and Oxidative Stress Induced by the Glyceraldehyde-related Maillard Reaction Products for HL-60 Cells; T. Usui, S. Shizuuchi, H. Watanabe, F. Hayase; Biosci. Biotechnol. Biochem. 2004; 68(2): 333-340. https://doi.org/10.1271/bbb.68.333
Isolation and Identification of the 3-Hydroxy-5-hydroxymethyl-pyridinium Compound as a Novel Advanced Glycation End Product on Glyceraldehyde-related Maillard Reaction; T. Usui, F. Hayase; Biosci. Biotechnol. Biochem. 2003; 67(4): 930-932. https://doi.org/10.1271/bbb.67.930
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