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Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorChemical name: (2S)-2-amino-5-(carbamimidoylsulfanyl)pentanoic acid hydrochloride salt // Synonyms: (S)-2-amino-5-(carbamimidoylthio)pentanoic acid hydrochloride salt, Thioarginine*HCl
from $250.00
Maillard Reaction Products (MRPs) are indicators for the heat treatment of food, as well as markers of nutritional quality. They also appear naturally in the human body as so-called Advanced Glycation End Products (AGEs). As such, they are indicators for body health and disease processes, including inflammation, diabetes, cancer and ageing. Consequently, AGEs gained broad attention in cosmetics, biochemistry, food, and pharmaceutical applications.
This material is supplied as a salt containing varying contents of the acid counterion. The net content of each batch is specified in the respective certificate of analysis.
Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with N-omega-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and L-ornithine. Thioarginine is a colorimetric substrate for arginase that provides the basis for continuous spectrophotometric measurement of enzyme activity. It exhibits Km and kcat values of 0.5 mM and 18,000 min-1, respectively, which are similar to physiological substrate arginine. The thiol product of the reaction reacts with DTNB to produce 2-nitro-5-thiobenzoate for easy visualization at 405-420 nm.
Amino acid discrimination by arginyl-tRNA synthetases as revealed by an examination of natural specificity variants; G. L. Igloi and E. Schiefermayr; FEBS J 2009; 276: 1307-18. https://doi.org/10.1111/j.1742-4658.2009.06866.x
Synthesis and evaluation of alternative substrates for arginase; S. Han, R. A. Moore and R. E. Viola; Bioorg Chem 2002; 30: 81-94. https://doi.org/10.1006/bioo.2001.1228
A spectrophotometric assay of arginase; S. Han and R. E. Viola; Anal Biochem 2001; 295: 117-9. https://doi.org/10.1006/abio.2001.5189
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