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2-SC
Chemical name: S-(2-Succinyl)-L-cysteine (mixture of two diastereoisomers) // Synonyms: S-(1,2-dicarboxyethyl)-L-cysteine, (R)-2-(2-amino-2-carboxyethylthio)succinic acid
- Product code:HAA3060
- CAS No.:547764-73-8
- Formula:C7H11NO6S
- Molecular weight:237.23 g/mol
from $231.25
description
Maillard Reaction Products (MRPs) are indicators for the heat treatment of food, as well as markers of nutritional quality. They also appear naturally in the human body as so-called Advanced Glycation End Products (AGEs). As such, they are indicators for body health and disease processes, including inflammation, diabetes, cancer and ageing. Consequently, AGEs gained broad attention in cosmetics, biochemistry, food, and pharmaceutical applications.
This material is supplied as a salt containing varying contents of the acid counterion. The net content of each batch is specified in the respective certificate of analysis.
references
Aspartyl and Glutamyl Peptides and the Acidic Cysteine Derivatives in Asparagus (Asparagus officinalis) Shoots; T. Kasai, Y. Hirakuri and S. Sakamura; Agricultural and Biological Chemistry 2014; 45: 433-437. https://doi.org/10.1080/00021369.1981.10864519
S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate; N. L. Alderson, Y. Wang, M. Blatnik, N. Frizzell, M. D. Walla, T. J. Lyons, N. Alt, J. A. Carson, R. Nagai, S. R. Thorpe and J. W. Baynes; Archives of biochemistry and biophysics 2006; 450: 1-8. https://doi.org/10.1016/j.abb.2006.03.005
Optical Resolution of (RS)-Mercaptosuccinic Acid and Syntheses of Four Stereoisomers of 2-Amino-3-1(1,2-dicarboxyethyl)sulfanyl)propanoic Acid; T. Shiraiwa, M. Ohkubo, M. Kubo, H. Miyazaki, M. Takehata, H. Izawa, K. Nakagawa and H. Kurokawa; Chemical & Pharmaceutical Bulletin 1998; 46: 1364-1369. https://doi.org/10.1248/cpb.46.1364
(2R), (1'R) and (2R), (1'S)-2-amino-3-(1,2-dicarboxyethylthio)propanoic acids from Amanita pantherina. Antagonists of N-methyl-D-aspartic acid (NMDA) receptors; S. Fushiya, Q. Q. Gu, K. Ishikawa, S. Funayama and S. Nozoe; Chem Pharm Bull (Tokyo) 1993; 41: 484-6. https://doi.org/10.1248/cpb.41.484
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