Custom Synthesis of Clicky Acids - Fatty Acids for Click Conjugation

Published on 21/11/2014

Fatty Acids for Click Conjugation

Fatty acid residues and alkyl chains in general can improve solubility and anchoring in membranes and other Lipophilie environments.

Find a selection of promptly available short and long chain clickable acids in our web store. Any other – including functional groups for copper-free Click conjugation can be made on custom synthesis basis.

Fatty Acids for Click Conjugation

Fatty acid residues and alkyl chains in general can improve solubility and anchoring in membranes and other lipophilic environments. Find a selection of promptly available short and long chain clickable acids in our web store.Any other derivative with alkyl chain of different length and including functional groups for copper- free Click conjugation – can be made on custom synthesis basis.

Any amino group bearing compound can be transferred into an analogue which can be used for Click conjugation. omega-Amino alkyl carboxylic acids can thus be converted into bicyclo[6.1.0]non-4-yn-9-yl (BCN) function carrying linkers, which can be used in any bioconjugation and related copper-free click reactions.The tetrazine moiety is the pendant to the azido group, while Diels-Alder conjugation also with linear alkyne functions happens without any need of further catalyst (copper or ruthenium) resulting in a pyridazine linking unit.