Product Focus

  1. Polylysines

    Polylysines are polymers of the canonical amino acid Lysine, and are characterized by their high charge density caused by the presence of one free amino group per lysine monomer.

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  2. Coupling Reagents for Peptide Chemistry

    In this news section, we highlight three useful coupling reagents for peptide chemistry: PyCLOCK, PyAOP and HDMA.

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  3. Triamino Acids

    Fmoc-L-Dap(2-Boc-aminoethyl)-OH is the first in a series of new triamino acid building blocks. This azalysine is useful for introducing positive charges into a peptide, or for creating branched structures.

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  4. Photocleavable NCL-Auxiliary Glycine

    This innovative auxiliary facilitates Native Chemical Ligation at the position of a Glycine residue in a peptide sequence. The auxiliary can be further functionalized, e.g. by PEGylation. Following NCL, the auxiliary is removed by irradiation with UV light.

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  5. Building Blocks for the SPPS of FRET-based fluorogenic protease substrates

    The classic FRET pair EDANS and DABCYL is now available linked to Fmoc amino acid building blocks that can be readily used in SPPS. Conveniently synthesize your own custom protease substrates!

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  6. Omniligase-1 for Efficient Peptide Ligation

    Omniligase-1 enables efficient and racemization-free ligation of two side-chain unprotected peptide fragments at many different positions. Test this innovative enzyme developed by EnzyPep B.V. using the complementary model peptides included in our kit!

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  7. The Safety-Catch Acid-Labile (SCAL)-Linker

    The SCAL linker offers superior chemical stability and permits a variety of orthogonal solid-phase approaches. It is fully compatible with the Fmoc-, Boc- and Alloc- strategies. Cleavage can be performed either by a simultaneous, or by a two-step reduction/acidolysis procedure to afford peptide amides.

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  8. New Iris Kits for the Synthesis of Peptoids and N-Alkylated Peptides

    Peptides as pharmaceutical compounds suffer from unfavorable pharmacokinetics which is, among other things, due to a slow uptake into cells and rapid proteolytic cleavage. N-Alkylation of peptides is a valuable tool to overcome these limitations. We now offer new kits that enable the facile preparation of peptoids and N-alkylated peptides.

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  9. Chlorotoxin & Biotin-Chlorotoxin

    Chlorotoxin is a chloride channel blocker which has been found in the venom of the Egyptian scorpionLeiurus quinquestriatus.

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  10. Fast and Easy Protease Kinetics with Asymmetric Rhodamine 110 Substrates

    Asymmetric Rhodamine 110 protease substrates are used for the determination of protease kinetics. The asymmetric structure of these dyes greatly simplifies the determination of enzyme kinetics, while the properties of Rhodamine 110 facilitate an uncomplicated readout.

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