Search results for: 'tom'

New Maillard Products for Peptide Synthesis and Analytics

Benefit of our latest Maillard Reaction Product additions! Use them as...

HMPO: A pH-Responsive Linker for Targeted Drug Delivery

HMPO (5-(hydroxymethyl)pyrogallol orthoester), a plasma-stable, pH-sensitive,...

PotM: MYTsA – A Novel Ynamide Coupling Reagent

Discover MYTsA as coupling reagent for peptide synthesis in “traditional”...

Hidden Champion – The Tetrahydropyranyl Protective Group

Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and...

GGFG Motif for ADC Construction

To address both chemical and IP considerations in self-immolating linker...

PotM: Versatile TentaGel® Resins

Discover the diversity of TentaGel® Resins! Read our blog to get more...

PotM: Cyclover-Amine for Peptide and Oligonucleotide Synthesis

Cyclophase Synthesis - Dissolve. React. Precipitate. Filter. Repeat! Make...

Protecting Groups in SPPS

Mix & Match. Discover typically employed protecting groups used to...

Amino-Li Resin – A Novel Solid Support

Shaken, not stirred. Amino-Li resin – a cross-linked polyacrylic amide...

Deprotection and Coupling in SPPS

Get the most out of your synthesis! Monitor your deprotection and coupling...

Bifunctional TentaGel® Resins

Encode beads with unique tags for combinatorial syntheses & screening....

Boc versus Fmoc for Solid Phase Peptide Synthesis

Wondering about the difference between Boc and Fmoc chemistry in solid phase...

Norbornenes – Will You Click Me?

Proposing norbornenes – strained, bicyclic alkenes for fast, copper-free,...

PotM: About the Impact of Fluorinated Building Blocks

Clever Move - Add positive effects to your molecule by introducing the most...

Carboxymethyl Amino Acid Derivatives

Level up! Carboxymethyl-modified amino acid building blocks suitable for...

“Power On” – Activity Control by Photocaging

Discover photocages – photosensitive protecting groups that are removed by...

Azobenzene Photoswitches

Engineer shape-shifting peptides, controllable by a laser as magic wand! In...

PotM: Oligomeric Sarcosine Building Blocks

You are looking for monodisperse Sarcosines? You want to use Sarcosine for...

Phenylboronate Amino Acid Building Blocks

Boron is not boring at all! Today, we'll delve deeper into the exciting world...

Linkerology® - An Example of Advanced Conjugation

The targeted delivery and traceless release of drugs is an important concept...

Phenylisopropylester (OPP) as Carboxy Protecting Group

Explore phenylisopropylesters (OPP/OPis) as carboxy protecting groups....

PotM: Aminoprolines - Controlling the Folding

You are looking for a building block suitable to control the folding...

A Tetrazole-Substituted Lysine as PTM Isostere

The tetrazole isostere of malonyllysine is thermally stable and does not...

Tougher Restrictions on DMF

REACH regulation for the handling of N,N-dimethylformamide (DMF), the most...

PotM: SCF3 in One

Increase your peptide’s stability, introduce an NMR label for analysis, or...

Special Deal: Amino Acid Bundle

Our special Christmas offer is still valid! Get our standard L-amino acid...

Review – Product Highlights 2023

Curious about the highlights of our 2023 portfolio additions? Discover...

Workshop on Click Chemistry in the Context of Automated Peptide Synthesis

You missed our workshop featuring Dr. Quibria Guthrie (CEM Corporation)? Any...

Special Christmas Offer!

Do not miss our special Christmas offer starting on December 1st!

Glycosylated Asparagine Building Blocks for SPPS

Add glycans to your proteins with our ready-to-use Fmoc asparagine building...

Automated Peptide Synthesis

The discovery of the Merrifield peptide synthesis paved the way for automated...

PotM: Small-sized, neutral fluorogenic amino acids suitable for SPPS

Discover our small-sized, neutral Fmoc-protected nitrobenzoselenadiazole- and...

Peptide Nucleic Acids as Stable DNA and RNA Analogs

One molecule, two identities: PNAs are composed of nucleobases arranged on a...

PotM: Next Generation Lysine Side Chain Protecting Groups

Sick of Lysine side chain protecting groups jumping around, yielding...

Linkerology® on Metal & Ore Surfaces

A heart of gold! Metals and ores - see here how their surfaces can be...

Process Development – From Discovery to Scale-up

Ongoing research efforts lead to the discovery of innovative building blocks...

Selective Lysine Labeling with Squaric Acid

Keeping control! PEGylating reagents with a squaric acid ethyl ester react...

PotM: Multiconjugates via Simultaneous Double-Click Reaction

Discover our new building block 4-(azido-propyl-tetrazine)phenylalanine...

Cell-Free Bioengineering & Linkerology®

Bioengineering in combination with Linkerology®. Check out the unique...

PotM: TCEP as Versatile Reducing Agent

TCEP is an effective reductant for disulfide bonds and a versatile reagent...

Functionalization of Carbon Materials by Linker Attachment

Allotropes of carbon show distinct characteristics in structure and e.g....

Cyanobenzothiazole (CBT) Derivatives for “Click” Conjugation

Discover the cyanobenzothiazole (CBT) click reaction, a not (yet) so...

Review – Product Highlights 2023 (Part 1)

Curious about our latest portfolio additions from January to June 2023?...

PotM: Safety Catch - Orthogonally Protected Amino Acids

Add a new dimension of orthogonality to your peptide synthesis by using...

Photoaffinity Labeling by Diazirine Building Blocks

Discover our diazirine-substituted building blocks suitable for the analysis...

Workshop Innovations in Click Chemistry

You missed our workshop featuring Prof. Rob Liskamp (Cristal Therapeutics,...

CliCr® - a Reactive and Soluble Bioorthogonal Click Reagent

Building blocks with a strained triple bond do not require copper catalysis...

PotM: Limited Offer - Polysarcosine Bundles

From beginning of May until end of July 2023 we offer special polysarcosine...

Conjugating Natural Products (1)

From evolution to solution - natural products are an infinite source of...

PotM: Functionalized Dextrans

Our monofunctionalized dextrans are enriching the toolbox of polymer...

Non-canonical Tryptophan Derivatives

Non-canonical Tryptophan analogs can help to improve your API’s performance...

Coupling Reagents

Coupling Reagents are required for the formation of an amide or ester bond....

Maleimide Crosslinkers

Maleimides provide versatile options for connecting payloads to proteins and...

Choose your Taste – Functionalized Halo/Snap/Clip Substrates

The HaloTag®, SNAP-Tag® and CLIP-TagTM represent versatile tools for the...

Temporary Activity Masking via Self-Immolative Linkage

(Bi)functional dioxoborolane and disulfide-based self-immolative linkers –...

Review – Product Highlights 2022

Curious about our latest portfolio additions from July to December 2022 and...

Abraligabra - Reagents and Building Blocks for Chemical Ligation

We can’t get enough of new products and innovations! Read this blog to get...

DTT and Spermidine for RNA Buffers and Vaccine Production

See how our “mRNA grade” DTT and Spermidine can support also your nucleic...

Linker Technologies for Sophisticated Bioconjugations

Linkers serve as versatile tools, e.g. during SPPS or for the sophisticated...

Everything for Nobel Chemistry

The 2022 Chemistry Nobel prize is awarded to B. Sharpless, M. Meldal and C....

PotM: Fmoc-Ser(Msbh)-OH

You are working on complex peptides and are looking for a new level of...

Process Development of SPPS

From mg synthesis of a peptide up to bulk quantities often makes a huge...

Impurities: Undesired, Unavoidable, Indispensable

No matter how much you hate them, in the pharmaceutical world you have to...

PotM: Smoc Amino Acids

Herein, we present the Clean Peptide Technology using Smoc Amino Acids...

PotM: Biotin – Desthiobiotin - Iminobiotin

Herein, we present 2-Iminobiotin, a cyclic guanidino analogue of biotin with...

pH-Sensitive Self-Immolative Linkers

Are you active in the field of antibody drug conjugates? Click here to find...

Workshop Polymer Therapeutics for Improved Drug Delivery

You missed our workshop featuring Prof. María Jesus Vicent Docón (Head of...

Peptide Easy Clean – Because Time Matters

We want to support you in the development of next generation peptide...

Drug Delivery at Iris Biotech

Discover our products suitable for drug delivery including poly...

Custom Synthesis Services at Iris Biotech

Iris Biotech is your trusted partner in the world of peptides and all related...

PotM: Proteolysis Targeting Chimeras (PROTACs®)

Drug the undruggable – click here to get more information about the use of...

Fatty Acid Building Blocks

We are providing variously functionalized, protected and unprotected fatty...

Amino Acid Oxidation Products

Oxidation is not only a known degradation pathway of proteins and peptides in...

Chemically Tunable Kinetics of Self-Immolation

Discover our selection of disulfide-based self-immolative linkers allowing to...

PotM: Functionalized Polysarcosines for the Formation of Lipid Nanoparticles: Towards Improved RNA Delivery

Interested in polymers for the delivery of promising drug candidates, e.g....

iNoc – An Acid Stable Alternative to Cbz

Looking for an acid stable protecting group? Struggling with undesired loss...

PotM: Substrates for Fusion (Halo/Snap/Clip)-Tagged Proteins

Discover our selection of substrates for Halo-, Snap-, and Clip-tagged...

Conformationally Constrained Amino Acid Derivatives

Herein we present a series of alpha,alpha-cycle-disubstituted amino acid...

PotM: About the Adamantyl Motif

Check out our growing portfolio on adamantyl-substituted amino acids and...

Haloalkane Dehalogenase Substrates

Discover our selection of Halo ligands as haloalkane dehalogenase substrates,...

PotM: Polysarcosines for Drug Delivery

Polysarcosines (PSars) – a true alternative to polyethyleneglycols (PEGs) -...

Refill your Chemical Stocks

Back in the lab after enjoying your holidays? Motivated to run new...

Maillard Reaction Products – General Advice for Usage, Reconstitution and Storage

Read on for more information about the right handling of Maillard Reaction...

PotM: Functionalized Biotinylation Reagents

Iris Biotech offers a variety of (functionalized) biotin and desthiobiotin...

N-Alkyl Substituted Carboxy Linkers for Peptide Synthesis

Herein, we present Fmoc-protected N-alkyl-substituted carboxy linkers, which...

Enzymatically Cleavable Linkers Based on Val-Cit and Val-Ala

The peptide-based ADC linkers Val-Cit and Val-Ala are efficiently cleaved by...

Trifluoromethylated Amino Acids

The incorporation of alpha-trifluoromethyl substituted amino acids into...

Clicky Acids – Fatty Acids for Click Conjugation

Iris Biotech offers various (protected) azide- and alkyne-modified fatty acid...

About the Advantages of Pseudoproline Dipeptides

Serine- and Threonine-derived oxazolidines as well as Cysteine-derived...

Thiol- and Amine Reactive Crosslinkers

Iris Biotech offers hetero-bifunctional crosslinkers bearing an...

PotM: Pyridyldithiols as Precursors for Disulfide-Based (Self-Immolative) Linkers

Read on to find out more about Iris Biotech’s Linkerology® portfolio...

PotM: Guanidino-Proline as rigid Arginine mimic

Interested in structure activity studies on your Arginine containing peptide...

DACNs for Strain-Promoted Azide-Alkyne Cycloadditions (SPAAC)

Herein we present substituted diazacyclononynes (DACNs) as versatile tools...

Adamantyls are a Chemist’s Best Friend

The highly lipophilic, bulky adamantyl motif is a promising and validated...

Aminooxy-Amino Acid Derivatives

Herein, we present aminooxy-amino acids reported for peptide synthesis via...

Arginine Derivatives Suitable for Side-Chain Derivatization

Herein we present two arginine derivatives, in which the native guanidino...

PotM: Disulfide-Based Self-Immolative Linkers

The linkage of a drug to its carrier via a disulfide-based self-immolative...

VIRTUAL BPS

January 19, 2021

Amino-Methylcoumarins as Fluorescent Labels

Enzymatically-activatable probes based on 7-amino-4-methylcoumarin (AMC)...

Product of the Month: Fluorinated Amino Acids

One approach for the design of bioactive peptides with improved...

Deamino- and Decarboxy-Histidine Derivatives

Interested in histidine derivatives? Iris Biotech provides a selection of...

Valine-Citrulline Based Enzymatically Cleavable Linkers

Iris Biotech presents its selection of Val-Cit-based linkers, a dipeptide...

Product Focus: Next Generation Phosphoamino Acid Analogs

Iris Biotech presents the next-generation of hydrolysis-stable...

Product Focus: Arginine Derivatives

Looking to optimize or functionalize your peptide? Explore our ever-growing...

Product of the Month: Novel Fmoc-Amino Acids for Convenient Access to HDAC Inhibitors

Find out more about those building blocks with side chains able to coordinate...

Identification and Quantification of Maillard RPs

Find out which Maillard Reaction Products from Iris Biotech were used in the...

Product of the Month: Dde-based Linkers

Placing Dde as one terminal group of a linker and a functional group prone...

Social Media Reloaded

Empowering Peptide Innovation – now also via Twitter! Iris Biotech is...

Subject Focus: Linkerology

The ever-growing sophistication and variation in linker design have given...

Alkyne Amino Acids for Click Chemistry and other Conjugations:

Alkyne amino acids allow for Click conjugations and other types of chemistry....

Product of the Month: cyclo-Arg-Gly-Asp (RGD) Peptides

The integrin receptor interacting RGD sequence and related peptides act as...

Product of the Month: “Cleland’s Reagent” Dithiothreitol (DTT)

DTT is a powerful yet mild reducing agent. Based on your demand we can offer...

Phenyl-, Cyclohexyl- and BCP-Amino Acids

Sidechain-derivatized amino acids have shown great potential in enhancing...

Lipidated Amino Acids

The tremendous success of Liraglutide and Semaglutide has moved amino acids...

PotM: Bicyclo[1.1.1]pentanes as Phenyl Ring Bioisosteres

The presence of phenyl groups in APIs is connected with various...

Statement on COVID-19

Beginning of March 2020 Iris Biotech implemented measures in order to...

4th GFPP Chemical Ligation Meeting

27 - 29 January 2020

Product of the Month: Biotin-Aniline for Proximity Labeling of RNA

Proximity labeling of proteins with biotin-phenol (biotin-tyramide) and an...

Diazirine Amino Acids: Photocrosslinking Applications

Two selected publications were summarized in this article in order to...

13th Australian Peptide Conference

8 - 13 September 2019

Protease Inhibitors

Protease inhibitors are molecules that inhibit protease function by binding...

Membrane-Impermeant Biotin Tyramide

Methods for proteomic mapping of cellular organelles or subdomains that avoid...

Fmoc-L-Lys(Nvoc)-OH

o-Nitroveratryloxycarbonyl (Nvoc) is a photocleavable side chain protecting...

H-L-Lys(Suc)-OH*HCl

Succinylation of proteins on the epsilon-amino group of lysine residues is a...

Product of the Month: Indocyanine Green (ICG) Dyes

Indocyanine Green (ICG) dye, a material approved by the FDA for various...

A Cyclo-RGD Peptide for the Preparation of Tumor Mimics

The 2D monolayer cell culture model is widely applied for drug screening....

Diazirine Amino Acids for Photo Cross-Linkage in Living Cells

Iris Biotech introduces a comprehensive set of photo-crosslinking amino acids...

How can I order?

Which payment methods are available?

Polyarginine

Polyarginines are well known for their ability to enhance cell penetration.

Polylysines

Polylysines are polymers of the canonical amino acid Lysine, and are...

Mercapto-PEG-Acids for Bioconjugation

Mercapto-PEG-Acids are highly hydrophilic, non-antigenic, non-immunogenic and...

2nd Generation Click Chemistry

Trifluoromethylated and other Fluoro-amino acids

The incorporation of trifluoromethyl group carrying building blocks into...

Specific Linkers

The variations for linkers are endless, as in our catalogue program already...

Spermines, spermidines and other Polyamines

Polyamines such as ethylene diamine and its higher homologues are important...

Polysarcosine – a True Alternative to PEG

Potential alternatives to PEGs, polypeptoids in general and polysarcosine...

Lysine Dendrons

We now offer a series of Lysine dendrons for chemoselective functionalization...

PEG-Conjugates of Folic Acid and Cholesterol

Conjugates of PEG and folic acid or cholesterol, respectively, combine the...

The 7th World ADC Conference

10-13 October 2016San Diego, CA, USAMarriot Marquis & Marina

Building Blocks for the SPPS of FRET-based fluorogenic protease substrates

The classic FRET pair EDANS and DABCYL is now available linked to Fmoc amino...

Omniligase-1 for Efficient Peptide Ligation

Omniligase-1 enables efficient and racemization-free ligation of two...

The Safety-Catch Acid-Labile (SCAL)-Linker

The SCAL linker offers superior chemical stability and permits a variety of...

New Iris Kits for the Synthesis of Peptoids and N-Alkylated Peptides

Peptides as pharmaceutical compounds suffer from unfavorable pharmacokinetics...

3rd Generation Click Chemistry: Tetrazine and TCO Derivatives for Copper-free Conjugation

The reaction between a tetrazine (Tz) and a trans-cyclooctene (TCO) is the...

Markers for the Quality of Food

Maillard Reaction Products (MRPs) result from the reaction of Arg and Lys...

Siderophore Building Block: New Hydroxamate-Ornithine for Fmoc/tBu SPPS

Nδ-hydroxy-Nδ-acetyl-ornithine, an important constituent of many...

Click Chemistry Tools: Propargyl Amino Acids

Click chemistry is a convenient method to chemoselectively functionalize...

Canalin and Canavanine : New Fmoc building blocks for novel peptides and protein analogs

5-oxa-Derivatives of Orn and Arg, respectively, these rare amino acids are...

New Substituted Ornithine Derivatives

l-Ornithine derivative containing peptides play important roles in SAR...

Locked and Loaded: Prepacked Fmoc-Amino Acids for ABI Synthesizers

Pre-packed amino acid cartridges for ABI peptide synthesizers are available...

Getting Bulky

Bulky glycine analogs are interesting molecules for creating peptide...

The 11th Australian Peptide Conference

October 25 to 30, 2015Peppers Salt & Spa, Kingscliff, NSW,...

CPhI worldwide 2015

October 13th - 15th, 2015Feria de Madrid, Spain Join us in Paris for CPhI...

NGlyO – for beta sheet formation

Surprising behavior of NXO-peptides. It is a significant property of peptides...

Peptide Solutions Appointed as Distributor for Iris Biotech for all North American Sales

We at Iris Biotech, are pleased to announce that we have entered into an...

Amino Aldehydes

Aldehydes are between alcohols and carboxylic acids with respect to their...

Linkers for Antibody-Drug Conjugation (ADC)

Cleavable dipeptide linkers like Val-Ala and Val-Cit rely on processes inside...

Stable Conjugation with Thiols

Maleimide (MAL) reacts rather specific with free thiol groups and forms...

Custom Synthesis of Clicky Acids - Fatty Acids for Click Conjugation

Fatty Acids for Click Conjugation Fatty acid residues and alkyl chains in...

The NEW Iris Biotech Catalogue is available now!

In the era of internet a printed edition of a catalogue still has some...

CPhI worldwide

October 7th - 9th, 2014Paris Nord VillepintParis, France Join us in Paris for...

Custom Synthesis of Alkyne Amino Acids Analogues for Click Conjugation

1,4-substituted 1,2,3-triazole are isosteric to peptide bonds and result in...

Custom Synthesis of Click-able compounds for Cu-free Click Conjugation

The presence of catalytic copper, limits the in vivo application of the Click...

Custom Synthesis of beta & gamma Amino Acids including Statine Analogues

GABA is a neurotransmitter in the central nervous system of mammals and its...

Benzotriazole Amino Acids

Benzotriazol activated carboxylic acids: Fast reaction (within minutes) at...

Aspartic and Glutamic Acid Homologues

Arginine rich peptides show increased interest during the last years as the...

Biotin Tyramide Reagents for Tyrosine-/Protein-Biotinylation

Tyramine compounds are converted to highly reactive radicals by horseradish...

MiDye is YOUR Dye!

Superior Performance at a Sensational Price! Available as –COOH, -NHS,...

Diamines & Polyamines

Compounds like putrescine, spermidine, and spermine play important roles in a...

The 2014 Belgian Peptide Group Meeting

February 10th-11th, 2014Ghent, Belgium This meeting intends to cover various...

Product of the Month: Fmoc-L-Cys(Dpm)-OH

Any amino acid can be functionalized on the N-terminus with oxalic acid and...

Perfluorophenyl azides as Photo Cross-Linker

Aryl azides are well-known precursors of nitrenes and have been introduced by...

A Total New Game for the Synthesis of Disulfide-Containing Peptides

The overall goal of our research is to capitalize on peptides of natural...

32nd European Peptide Symposium

September 2nd - 7th, 2012Athens, GreeceMegaron Conference Centre   With...

Cross-Linker: Mal-AMCHC-OSu

Mal-AMCHC-OSu trans-N-Succinimidyl...

The concept of internal solubilization in peptide synthesis: ethylene glycol-based protecting groups

A novel, ethylene glycol-based protecting group is designed and synthesized...