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Boc-L-Lys(Mtt)-OH*DCHA
Chemical name: N-alpha-t-Butyloxycarbonyl-N-epsilon-(4-methyltrityl)-L-lysine dicyclohexylamine // Synonyms: Boc-Lys(Mtt)-OH*DCHA
- Product code:BAA5070
- CAS No.:2227225-16-1 net
- Formula:C31H38N2O4*C12H23N
- Storage temperature:2-8°C
- Molecular weight:502.64*181.32 g/mol
from $887.50
description
Building block with side protection orthogonal to Fmoc/tBu strategy. Can be used for side specific derivatization, for example for TFA mediated in situ cyclization, which is taking advantage of intermediate aspartamide formation.
references
A Tandem In Situ Peptide Cyclization through Trifluoroacetic Acid Cleavage; Koushik Chandra, Tapta Kanchan Roy,
Deborah E. Shalev, Abraham Loyter, Chaim Gilon, R. BennyGerber, and Assaf Friedler; Angew. Chem. Int. Ed. 2014;
53: 9450-9455. DOI: 10.1002/anie.201402789.
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