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Fmoc-Gly-Sulfamoylbenzoic Acid
Chemical name: 4-(N-alpha-(9-Fluorenylmethoxycarbonyl)-glycyl-sulfonyl)benzoic acid // Synonyms: 4-[2-(9H-Fluoren-9-ylmethoxycarbonylamino)-acetylsulfamoyl]-benzoic acid, 4-[[[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetyl]amino] sulfonyl]-benzoic acid
- Product code:RL-3620
- CAS No.:881913-43-5
- Formula:C24H20N2O7S
- Storage temperature:2-8°C
- Molecular weight:480.49 g/mol
from $218.75
description
N-Acyl Sulfonamides are useful products for medicinal chemistry, solid support linking strategies, and for conjugation and ligation applications.
references
Thio Acid/Azide Amidation: An Improved Route to N-Acyl Sulfonamides. K. N. Barlett, R. V. Kolakowski, S. Katukojvala, and L. J. Williams; Org. Lett. 2006; 8; 823-826. https://doi.org/10.1021/ol052671d
An Alkanesulfonamide Safety-Catch Linker for Solid-Phase Synthesis; B. J. Backes and J. A. Ellman; The Journal of Organic Chemistry 1999; 64: 2322-2330. https://doi./org/10.1021/jo981990y
Safety-catch and multiply cleavable linkers in solid-phase synthesis; M. Pátek and M. Lebl; Biopolymers 1998; 47: 353-363. https://doi.org/10.1002/(SICI)1097-0282(1998)47:5<353::AID-BIP3>3.0.CO;2-I
Activation Method to Prepare a Highly Reactive Acylsulfonamide Safety-Catch Linker for Solid-Phase Synthesis1; B. J. Backes, A. A. Virgilio and J. A. Ellman; Jo urnal of the American Chemical Society 1996; 118: 3055-3056. https://doi.org/10.1021/ja9535165
The safety catch principle in solid phase peptide synthesis; G. W. Kenner, J. R. McDermott and R. C. Sheppard; Journal of the Chemical Society D: Chemical Communications 1971: 636-637. https://doi.org/10.1039/c29710000636
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