Fmoc-L-Asp(OtBu)-MPPA

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid beta-t-butyl ester-3-(4-oxymethylphenoxy)propionic acid // Synonyms: (S)-3-(4-(((2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)oxy)methyl)phenoxy)propanoic acid,1-[[4-(2-Carboxyethoxy)phenyl]methyl]-4-(1,1-dimethylethyl)-N-[(9H-fluoren-9 -ylmethoxy)carbonyl]-L-aspartate, Fmoc-Asp(OtBu)-M

  • Product code:LW00402
  • CAS No.:864876-94-8
  • Formula:C33H35NO9
  • Molecular weight:589.64 g/mol

from $118.75

Grouped product items
Qty Packing unit Price SKU Availability
1 g
$118.75
LW00402.0001
<10 business days
5 g
$468.75
LW00402.0005
<10 business days
description

This Fmoc-amino acid-MPPA linker serves as precursor for the linkage to e.g. aminomethyl supports by standard coupling procedures. By this method, a low (max 0.5%) and reproducible epimerization level of the C-terminal amino acid in your peptide is guaranteed.


references

Improved approach for anchoring Nalpha-9-fluorenylmethyloxycarbonylamino acids as p-alkoxybenzyl esters in solid-phase peptide synthesis; F. Albericio, G. Barany; Int. J. Peptide. Protein. Res. 1985; 26(1): 92-97. https://doi.org/10.1111/j.1399-3011.1985.tb03182.x.


Amino acid derivatives used as agents bonding to a solid support; NeoMPS S.A. 2005; French Patent Application FR 0402973, International Patent Application WO2005/095332.

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