Fmoc-NH-MsbH-COOH

Chemical name: 5-(2-((((9H-fluoren-9-yl)methoxy)carbonylamino)(4-(methylsulfinyl)phenyl)methyl)-5-(methylsulfinyl)phenoxy)pentanoic acid // Synonyms: Safety-Catch-Acid-Sensitive Linker, 5-(2-((Fmoc-amino)(4-(methylsulfinyl)phenyl)methyl)-5-(methylsulfinyl)phenoxy)pentanoic acid, Fmoc-amino-di(methylsulfinyl)benzhydryl linker,SCAL-Linker

  • Product code:RL-2260
  • CAS No.:147046-64-8
  • Formula:C35H35NO7S2
  • Molecular weight:645.78 g/mol

from $187.50

Grouped product items
Qty Packing unit Price SKU Availability
250 mg
$187.50
RL-2260.0250
<10 business days
1 g
$562.50
RL-2260.0001
<10 business days
5 g
$2,250.00
RL-2260.0005
<10 business days
Safety Data Sheets
description

This reagent may be used to build molecules with a free amino group upon release. The pentanoic acid residue can be used to immobilize the SCAL-Linker via an ester or amide on a resin or carrier molecule. The amino group is liberated by reduction of the sulfoxides, followed by acidolysis with TFA.

references

Safety-catch and multiply cleavable linkers in solid-phase synthesis; M. Pátek and M. Lebl; Biopolymers 1998; 47: 353-363. doi:10.1002/(sici)1097-0282(1998)47:5<353::Aid-bip3>3.0.Co;2-i

Safety-catch anchoring linkage for synthesis of peptide amides by Boc/Fmoc strategy; M. Pátek and M. Lebl; Tetrahedron Letters 1991; 32: 3891-3894. doi:10.1016/s0040-4039(00)79406-8


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