Fmoc-L-Ser(tBu)-MPPA

Chemical name: N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-serine-3-(4-oxymethylphenoxy)propionic acid // Synonyms: 3-(4-(((N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-seryl)oxy)methyl)phenoxy)propanoic acid,O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine-[4-(2-carboxyethoxy)phenyl ]methyl ester, Fmoc-Ser(tBu)-MPPA

  • Product code:LW01602
  • CAS No.:864876-96-0
  • Formula:C32H35NO8
  • Molecular weight:561.63 g/mol

from $118.75

Grouped product items
Qty Packing unit Price SKU Availability
1 g
$118.75
LW01602.0001
<10 business days
5 g
$468.75
LW01602.0005
<10 business days
description

This Fmoc-amino acid-MPPA linker serves as precursor for the linkage to e.g. aminomethyl supports by standard coupling procedures. By this method, a low (max 0.5%) and reproducible epimerization level of the C-terminal amino acid in your peptide is guaranteed.


references

Improved approach for anchoring Nalpha-9-fluorenylmethyloxycarbonylamino acids as p-alkoxybenzyl esters in solid-phase peptide synthesis; F. Albericio, G. Barany; Int. J. Peptide. Protein. Res. 1985; 26(1): 92-97. https://doi.org/10.1111/j.1399-3011.1985.tb03182.x.


Amino acid derivatives used as agents bonding to a solid support; NeoMPS S.A. 2005; French Patent Application FR 0402973, International Patent Application WO2005/095332.

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