Welcome to Iris Biotech
For better service please confirm your country and language we detected.
For better service please confirm your country and language we detected.
Thank you very much for your interest in our products. All prices listed on our website are ex-works, Germany, and may attract customs duties when imported.
You may/will be contacted by the shipping company for additional documentation that may be required by the US Customs for clearance.
We offer you the convenience of buying through a local partner, Peptide Solutions LLC who can import the shipment as well as prepay the customs duties and brokerage on your behalf and provide the convenience of a domestic sale.
Continue to Iris Biotech GmbHSend request to US distributorChemical name: 1-((tert-Butoxycarbonyl)amino)cyclooctane-1-carboxylic acid // Synonyms: 1-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclooctanecarboxylic acid
from $375.00
This derivative can be used as constrained building block for structure activity relationship studies. Such alpha,alpha-disubstituted amino acids are widely used in peptide design because of their structure promoting effects.
Preptin Analogues: Chemical Synthesis, Secondary Structure and Biological Studies; C. M. Buchanan, Z. Peng, A. Cefre, V. Sarojini; Chem. Biol. Drug Des. 2013; 82(4): 429-437. https://doi.org/10.1111/cbdd.12168.
Peptide helices with pendant cycloalkane rings. Characterization of conformations of 1-aminocyclooctane-1-carboxylic acid (Ac8c) residues in peptides; J. Pept. Sci. 2004; 10(3): 160-172. https://doi.org/10.1002/psc.507.
Agonist Activity at the Kinin B1 Receptor: Structural Requirements of the Central Tetrapeptide; P. Rovero, M. Pellegrini, A. Di Fenza, S. Meini, L. Quartara, C. A. Maggi, F. Formaggio, C. Toniolo, D. F. Mierke; J. Med. Chem. 2001; 44(2): 274-278. https://doi.org/10.1021/jm000319u.
A New Clas of Pseudopeptide Antagonists of the Kinin B1 Receptor Containing Alkyl Spacers; C. Galoppini, S. Meini, M. Tancredi, A. Di Fenza, A. Triolo, L. Quartara, C. A. Magi, F. Formaggio, C. Toniolo, S. Mazzucco, A. Papini, P. Rovero; J. Med. Chem. 1999; 42(3): 409-414. https://doi.org/10.1021/jm980495r.
Please send me more information about