Fmoc-Ac6c(4-Boc-NH)-OH

Chemical name: 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylic acid

  • Product code:FAA8630
  • CAS No.:914358-27-3
  • Formula:C27H32N2O6
  • Molecular weight:480.56 g/mol

from $1,125.00

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1 g
$1,125.00
FAA8630.0001
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description

This derivative can be used as constrained building block for structure activity relationship studies. Such alpha,alpha-disubstituted amino acids are widely used in peptide design because of their structure promoting effects.


references

Synthesis of six-membered carboyclic ring alpha,alpha-disubstituted amino acids and arginine-rich peptides to investigate the effect of ring size on the properties of the peptide; T. Kato, Y. Kita, K. Iwanari, A. Asano, M. Oba, M. Tanaka, M. Doi; Bioorg. Med. Chem. 2021; 38: 116111. https://doi.org/10.1016/j.bmc.2021.116111.


Synthesis of a series of polar, orthogonally protected, alpha,alpha-disubstituted amino acids; T. Scott Yokum, M. G. Bursavich, S. A. Piha-Paul, D. A. Hall, M. L. McLaughlin; Tetrahedron Lett. 1997; 38(23): 4013-4016. https://doi.org/10.1016/S0040-4039(97)00822-8.

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