Fmoc-Appc

Chemical name: 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-phenylpiperidine-4-carboxylic acid // Synonyms: Fmoc-Pip(Ph)-OH, Fmoc-4-amino-1-phenylpiperidine-4-carboxylic acid

  • Product code:FAA8640
  • CAS No.:365550-97-6
  • Formula:C27H26N2O4
  • Molecular weight:442.52 g/mol

from $1,125.00

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1 g
$1,125.00
FAA8640.0001
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description

This derivative can be used as constrained building block for structure activity relationship studies. Such alpha,alpha-disubstituted amino acids are widely used in peptide design because of their structure promoting effects.


references

Synthesis of six-membered carboyclic ring alpha,alpha-disubstituted amino acids and arginine-rich peptides to investigate the effect of ring size on the properties of the peptide; T. Kato, Y. Kita, K. Iwanari, A. Asano, M. Oba, M. Tanaka, M. Doi; Bioorg. Med. Chem. 2021; 38: 116111. https://doi.org/10.1016/j.bmc.2021.116111.

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