Boc-L-Tyr(3-CF3)-OH

Chemical name: N-alpha-t-Butyloxycarbonyl-3-trifluoromethyl-L-tyrosine // Synonyms: Boc-3-trifluoromethyl-L-tyrosine, (S)-2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3-(trifluoromethyl)phenyl)propanoic acid, Boc-Tyr(3-CF3)-OH

  • Product code:BAA4400
  • CAS No.:174748-28-8
  • Formula:C15H18F3NO5
  • Storage temperature:2-8°C
  • Molecular weight:349.31 g/mol

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references

Modulating OxyB-Catalyzed Cross-Coupling Reactions in Vancomycin Biosynthesis by Incorporation of Diverse d-Tyr Analogues; S. Ozturk, C. C. Forneris, A. K. L. Nguy, E. J. Sorensen and M. R. Seyedsayamdost; J Org Chem 2018; 83: 7309-7317. https://doi.org/10.1021/acs.joc.8b00916

Protecting group free radical C-H trifluoromethylation of peptides; N. Ichiishi, J. P. Caldwell, M. Lin, W. Zhong, X. Zhu, E. Streckfuss, H. Y. Kim, C. A. Parish and S. W. Krska; Chemical science (Royal Society of Chemistry : 2010) 2018; 9: 4168-4175. https://doi.org/10.1039/c8sc00368h

(18)F-Trifluoromethanesulfinate Enables Direct C-H (18)F-Trifluoromethylation of Native Aromatic Residues in Peptides; C. W. Kee, O. Tack, F. Guibbal, T. C. Wilson, P. G. Isenegger, M. Imiolek, S. Verhoog, M. Tilby, G. Boscutti, S. Ashworth, J. Chupin, R. Kashani, A. W. J. Poh, J. K. Sosabowski, S. Macholl, C. Plisson, B. Cornelissen, M. C. Willis, J. Passchier, B. G. Davis and V. Gouverneur; J Am Chem Soc 2020; 142: 1180-1185. https://doi.org/10.1021/jacs.9b11709

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