Publication

Synthesis of RGD Peptides Inducing Multicellular Spheroids Formation

In vitro assessment of the cytotoxic effects of novel RGD analogues and conjugates

Convenient method of peptide hydrazide synthesis using a new hydrazone resin

Peptide hydrazides can be easily synthesized using a new hydrazone resin, obtained via acylation of aminomethyl polystyrene by Fmoc-hydrazone of pyruvic acid.

Novel Disulfide Bond Formation Strategies in Solid-Phase Peptide Synthesis

Eco-Friendly Combination of the Immobilized PGA Enzyme and the S-Phacm Protecting Group for the Synthesis of Cys-Containing Peptides

Enzyme‐labile protecting groups have emerged as a green alternative to conventional protecting groups.

A Total New Game for the Synthesis of Disulfide-Containing Peptides

The overall goal of our research is to capitalize on peptides of natural origin and their biological activity and chemistry.

N-Fmoc-a-sulfo-b-alanine: a versatile building block for the water solubilisation of chromophores and fluorophores by solid-phase strategy

Abstract: An easy and efficient solid-phase synthesis strategy to obtain rapidly water-soluble chromophores/fluorophores in highly pure form has been developed.

Parallel Synthesis and Reaction Optimization

The concept of internal solubilization in peptide synthesis: ethylene glycol-based protecting groups

A novel, ethylene glycol-based protecting group is designed and synthesized for use in solid phase peptide synthesis.

Shorter Arginine homologues to stabilize peptides towards tryptic digestion

Abstract: Trypsin digests peptides at the position of arginine. Because shorter homologues of arginine with appropriate protecting groups for conventional Fmoc/tBu peptide synthesis are now available, three model peptides containing arginine and two shorter homologues of arginine were synthesized.