Amino Acids

  1. Carboxymethyl Amino Acid Derivatives

    Level up! Carboxymethyl-modified amino acid building blocks suitable for incorporation by solid-phase peptide synthesis. Learn more about available derivatives and their properties.

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  2. “Power On” – Activity Control by Photocaging

    Discover photocages – photosensitive protecting groups that are removed by irradiation with light of a defined wavelength, thus restoring the original, “active” state.

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  3. 2-Cyanopyridines for Click-Like Reactions

    Have an additional ace up your sleeve for selective and efficient peptide modification, cyclization, and/or bioconjugation. Explore 2-cyanopyridines for click-like reactions. Get more information!

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  4. Aminothiols for Versatile Side-Chain Modification

    Beyond cysteines: Unlock targeted side-chain modifications of your peptides and proteins via the introduction of 1,2-aminothiols and subsequent click-like functionalization. 

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  5. Azobenzene Photoswitches

    Engineer shape-shifting peptides, controllable by a laser as magic wand! In this newsletter, we’ll explore the possibilities of photo switchable building blocks based on azobenzene.

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  6. Phenylboronate Amino Acid Building Blocks

    Boron is not boring at all! Today, we'll delve deeper into the exciting world of boronate-containing amino acid building blocks and unlock the potential of the next generation of peptides. Read on!

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  7. Phenylisopropylester (OPP) as Carboxy Protecting Group

    Explore phenylisopropylesters (OPP/OPis) as carboxy protecting groups. Facilitate your peptide synthesis with building blocks for precise side chain modifications or seamless macrolactamizations. 

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  8. PotM: Aminoprolines - Controlling the Folding

    You are looking for a building block suitable to control the folding characteristics of your peptide or want to add a pH-sensitive conformational switch? Discover aminoprolines and their properties!

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  9. Fluorogenic Building Blocks for Peptide Guided Wash-Free Imaging

    Live-imaging of dynamic structures and catching events in living cells is a challenge, as most fluorescent probes have a high background signal. For alternatives, please read on!

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  10. PotM: Blockbuster Building Blocks

    Are you keen on developing novel billion-dollar-selling peptide API blockbusters? Most recent ones use lipophilic Albumin binding moieties. Of course, Iris Biotech has the necessary building blocks!

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