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Visit this regularly updated section to check out the latest additions to our portfolio, as well as the latest developments at Iris Biotech.
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Bis-Mal-Lysine
Bis Thiol & Amine reactive PEGylated Cross-Linker which has been used for enhanced receptor binding, for the design of long-acting conjugates for type 2 diabetes therapeutics and in reorienting the Fab Domains of Trastuzumab Results in Potent HER2 Activators.
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Phthalimidooxy PEG-based cross linkers
Phthalimidooxy PEG-based cross linkers form stable oximes with aldehydes, also latent ones as present in carbohydrates. Their reactivity is sufficiently mild for a broad used in creating conjugates with sensitive biologics.
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Prolines with Hydrophobic Substituents
Prolines are key elements positioned at the edge of β-turns in peptides. With modified prolines these positions can be used for either covalent amide or disulfide bonds – as we have demonstrated in many examples – or for filling hydrophobic pockets, whenever the pyrrolidine ring is substituted with groups like Methyl or Phenyl.
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MiDye is YOUR Dye!
Superior Performance at a Sensational Price!
- Available as –COOH, -NHS, -Maleimide, -Alkyne, -Azide
- Half the price of other well-known dyes like Alexa- & Cy-Dyes.
- Available also in large quantities.
- Broadly applied in cell imaging, FRET, fluorescence quenching.
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Diamines & Polyamines
Compounds like putrescine, spermidine, and spermine play important roles in a many biological functions. Many of them are excellent targets for oncology studies and other fields of medicinal chemistry.
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Find in our new brochure Diamines & Polyamines our possibilities for custom synthesis and a set over 100 available derivatives. -
Recap China Hi-Tech Fair 2013
Cfm Oskar Tropitzsch and Iris Biotech GmbH attended the China Hi-Tech-Fair (Nov 16-21, 2013) in Shenzhen. The Bavarian companies presented the latest stage of the art products in the field of peptides, life sciences research and drug discovery.
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Ellmans Reagent
DTNB, frequently called Ellman’s Reagent, used as reagent for determination of free sulfhydryl groups.
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New TentaGel XV (eXtended swelling Volume)
Resin especially designed for the synthesis of long and difficult peptide sequences!
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Product of the Month: Fmoc-L-Cys(Dpm)-OH
Any amino acid can be functionalized on the N-terminus with oxalic acid and on the C-terminus with hydrazine, in order to form a so-called NXO building block. Through this double modification N and C terminus will be inverted, which provides interesting structural options for peptidomimetics.
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Dess-Martin-Periodinane: Mild Selective Reagent for Oxidation of Alcohols
Dess-Martin-Periodinane is one of the most useful reagents for the reduction of primary and secondary alcohols to aldehydes and ketones.
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